Results 91 to 100 of about 1,566,362 (348)

A four stage evolution of the White Channel gravel: Implications for stratigraphy and palaeoclimates [PDF]

open access: yes, 2014
Although the White Channel gravel (WCG) of the Klondike district, Yukon, contains gold placers which have been exploited for over a century, few sedimentological studies have been undertaken.
Chapman, Robert   +3 more
core  

Synthesis and self-assembly of lipid (DMPC)-conjugated gold nanoparticles

open access: yes, 2007
Bio-conjugated nanomaterials play a promising role in the development of novel supramolecular structures, molecular machines, and biosensing devices. In this study, lipid-conjugated gold nanoparticles were synthesized and allowed to form a self-assembled
Chatterjee, Subhasish   +3 more
core   +1 more source

Synthesis of Cationic Gold(Iii) Complexes Using Iodine(Iii) [PDF]

open access: yesJournal of Coordination Chemistry, 2018
It is shown that halides are important in inducing scrambling in Au(III) coordination complexes, and that monodentate phosphines are less compatible than carbenes with Au(III)
Mohammad Albayer, Jason Dutton
openaire   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Proteomic characterization of the cytotoxic mechanism of gold (III) porphyrin 1a, a potential anticancer drug [PDF]

open access: yes, 2006
There has been increasing interest in the potential applications of gold (III) complexes as anticancer drugs with higher cytotoxicity and fewer side effects than existing metal anticancer drugs.
Che, CM, Chiu, JF, He, QY, Wang, Y
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

(C^Npz^C)AuIII complexes of acyclic carbene ligands: synthesis and anticancer properties [PDF]

open access: yes, 2017
A series of cyclometallated gold(III) complexes supported by pyrazine-based (C^Npz^C)-type pincer ligands were synthesized via two different pathways. Nucleophilic attack on the isocyanide complex [(C^Npz^C)Au(C≡NC6H3Me2-2,6)]SbF6 (2) gave [(C^Npz^C)Au ...
Bertrand, Benoit   +7 more
core   +2 more sources

Synthesis, Mesomorphism, Photophysics, and Device Properties of Liquid-Crystalline Pincer Complexes of Gold(III) Containing Semiperfluorinated Chains [PDF]

open access: gold, 2022
Rachel R. Parker   +7 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

X-ray Crystal Structures and the Facile Oxidative (Au−C) Cleavage of the Dimethylaurate(I) and Tetramethylaurate(III) Homologues [PDF]

open access: yes, 1999
Dimethylaurate(I) has been prepared as the crystalline tetrabutylammonium salt for comparison with the known tetramethylaurate(III) analogue. The linear structure of dimethylaurate(I) and the square-planar structure of tetramethylaurate(III) have both ...
Kochi, Jay K.   +2 more
core   +1 more source

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