Results 31 to 40 of about 62,853 (255)
The reaction of the ligand Et4todit (4,5,6,7-Tetrathiocino-[1,2-b:3,4-b']-diimidazolyl-1,3,8,10-tetraethyl-2,9-dithione) with gold complexes leads to the dinuclear gold(I) complexes [{Au(C6F5)}2(Et4todit)] and [Au(Et4todit)]2(OTf)2, which do not contain ...
Francesco Caddeo +5 more
doaj +1 more source
Gold Derivatives Development as Prospective Anticancer Drugs for Breast Cancer Treatment
Commonly used anticancer drugs are cisplatin and other platinum-based drugs. However, the use of these drugs in chemotherapy causes numerous side effects and the onset of frequent drug resistance phenomena.
Ileana Ielo +8 more
doaj +1 more source
Gold(I/III)-Phosphine Complexes as Potent Antiproliferative Agents
The reaction of gold reagents [HAuCl4•3H2O], [AuCl(tht)], or cyclometalated gold(III) precursor, [C^NAuCl2] with chiral ((R,R)-(-)-2,3-bis(t-butylmethylphosphino) quinoxaline) and non-chiral phosphine (1,2-Bis(diphenylphosphino)ethane, dppe) ligands lead
Jong Hyun Kim +3 more
doaj +1 more source
Reactions of gold(III) complexes with serum albumin [PDF]
The reactions of a few representative gold(III) complexes –[Au(ethylenediamine)2]Cl3, [Au(diethylentriamine)Cl]Cl2, [Au(1,4,8,11‐tetraazacyclotetradecane)](ClO4)2Cl, [Au(2,2′,2′‐terpyridine)Cl]Cl2, [Au(2,2′‐bipyridine)(OH)2][PF6] and the organometallic compound [Au(6‐(1,1‐dimethylbenzyl)‐2,2′‐bipyridine‐H)(OH)][PF6]– with BSA were investigated by the ...
MARCON G +4 more
openaire +3 more sources
Sorption processes on the surfaces of chemically modified silica gels containing both mercaptopropyl and aminopropyl groups were examined. It was established that gold(III) sorption on the surfaces of such heteroligand silica gels involved the formation ...
A.K. Trokhimchuk +2 more
doaj +1 more source
Recent advances in anticancer metallodrugs based on gold complexes and clusters
In the field of metal-based anticancer agents, gold-based drugs have emerged as one of the most promising research directions following platinum-based drugs, owing to their unique physicochemical properties and distinct anticancer mechanisms. This review
Xiaoni An, Liang Zhao
doaj +1 more source
Synthesis of Cationic Gold(Iii) Complexes Using Iodine(Iii) [PDF]
It is shown that halides are important in inducing scrambling in Au(III) coordination complexes, and that monodentate phosphines are less compatible than carbenes with Au(III)
Mohammad Albayer, Jason Dutton
openaire +1 more source
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Targeting aquaporin function: potent inhibition of aquaglyceroporin-3 by a gold-based compound. [PDF]
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many physiological functions. Aquaporin-based modulator drugs are predicted to be of broad potential utility in the treatment of several ...
Ana Paula Martins +8 more
doaj +1 more source
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source

