Results 61 to 70 of about 1,998,716 (326)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Open data, [open] access: linking data sharing and article sharing in the Earth Sciences
Journal of Librarianship and Scholarly Communication, 2017 INTRODUCTION The norms of a research community influence practice, and norms of openness and sharing can be shaped to encourage researchers who share in one aspect of their research cycle to share in another.
Samantha Teplitzky
doaj +2 more sources
Green and Gold Open Access Percentages and Growth, by Discipline [PDF]
, 2012 Most refereed journal articles today are published in subscription journals, accessible only to subscribing institutions, hence losing considerable research impact.
Carr, Les +4 more
core +1 more source
Recreating mineralogical petrographic heterogeneity within microfluidic chips : assembly, examples, and applications [PDF]
, 2016 This material includes work supported by Royal Society Research Grant RG140009. BA was supported by a Society of Petrophysics and Well Log Analysts (SPWLA) grant and an Aberdeen Formation Evaluation Society (AFES) bursary.
Akamairo, Blessing +3 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Open Access Week 2011 in the Czech Republic (Report)
Liber Quarterly: The Journal of European Research Libraries, 2012 The awareness of open access is slowly rising in the Czech academic environment. Both green open access and gold open access have broken through thanks to Open Access Week, which has for the second time been organized by twelve Czech university libraries,
Pavla Rygelová
doaj +1 more source
Redox potentials of aryl derivatives from hybrid functional based first principles molecular dynamics [PDF]
, 2016 Acknowledgements We acknowledge the National Science Foundation of China (No. 41222015, 41273074, 41572027 and 21373166), Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase), the Foundation for ...
Cheng, Jun +4 more
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source