Results 41 to 50 of about 6,602 (296)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Terrigenous Tertiary Gold Bearing Strata: World Distribution, Economic Significancy and Modern Placer Formation Capacity

Russian Journal of Earth Sciences
The article is dedicated to estimation of tertiary terrigenous strata role in world gold mining. Localization peculiarities of tertiary gold deposits and their placers were examined.
Vladimirceva Ol'ga, Lalomov Alexander, Prasolov Alexander, Orlov Sergei   +3 more
doaj   +1 more source

A Summary of gold fineness values from Alaska placer deposits [PDF]

, 1981
This report is the first in a series of publications by the Mineral Industry Research Laboratory and the Alaska Division of Geological and Geophysical Surveys under a special appropriation by the Alaska State Legislature to the School of Mineral Industry
Hawkins, D.B., Metz, P.A.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Applicability of siberian placer mining technology to Alaska [PDF]

, 1991
The result of Perestroyka and Glasnost has been an awakening of potential for cooperation between East and West. Nowhere has that been better demonstrated than between Alaska and Magadan Province, USSR. This report summarizes a one year effort financed
Barker, J.C., MacDonald, Rocky, Skudrzyk, F.J., Walsh, D.E.   +3 more
core  

Packaging technology enabling flexible optical interconnections [PDF]

, 2011
This paper reports on the latest trends and results on the integration of optical and opto-electronic devices and interconnections inside flexible carrier materials.
Bosman, Erwin, Kalathimekkad, Sandeep, Missinne, Jeroen, Van Daele, Peter, Van Hoe, Bram, Van Steenberge, Geert   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Distribution, analysis, and recovery of fine gold from alluvial deposits [PDF]

, 1973
The United States Bureau of Mines, in its Heavy Metals Program, desired to have research performed to determine the size-frequency distribution and possible economic value of gold particles in the fine size ranges of Alaskan placer deposits.
Cook, D.J., Rao, P.D.
core  

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Managing in situ gold concentrations in placers [PDF]

International Journal of Mining and Geo-Engineering, 2015
In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident.
Alexandr Mikhailov
doaj