Results 31 to 40 of about 1,140 (260)

Features of choosing the schemes for selective mining of ores and justifying their rational parameters while using heap leaching schemes for processing [PDF]

E3S Web of Conferences, 2020
The article presents data from theoretical and experimental studies related to the search for a solution to an urgent geotechnological problem - selective mining of standard quality ore, substandard and diluted ores, taking into account the peculiarities
Sekisov Gennady, Sobolev Aleksei, Ashimbaev Abdakim   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Mineralurgical and Environmental Characterization of the Mine Tailings of the IOCG Mine of Guelb Moghrein, Akjoujt, Mauritania

Applied Sciences
Since 2004, the processing of the iron oxide–copper–gold (IOCG) ore of Guelb Moghrein, Akjoujt, Mauritania, has resulted in the generation of approximately 40 million tons of mine tailings.
NDiarel Baidy Ba, Radhia Souissi, Faouzi Manai, Imad Khalil Taviche, Bochra Bejaoui, Mohamed Abdallahi Bagga, Fouad Souissi   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Study of Mercury and Arsenic Contamination in Gold Processing Tailings from Gunung Botak, Buru Island – Maluku

Indonesian Journal of Chemical Research
Buru Island in Maluku Province is one of the sites of unlicensed gold mining activities (Illegal Gold Mining, IGM), which may lead to environmental pollution due to improper waste management. This study aimed to analyze the concentrations of mercury (Hg)
Anto Netty Siahaya, Matheis Frits Jan David Pieter Tanasale, Shielda Natalia Joris, Muhammad Syahyono Hasimin, Filky Sky Choesni   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The use of sequential extraction procedure for mercury fractionation study in gold mining tailings: implications for environmental pollution

Journal of Degraded and Mining Lands Management
Artisanal and small-scale gold mining (ASGM) activities still use mercury (Hg) for the amalgamation processing step. These ASGM activities generate tailings as a mining by-product, representing the primary source of environmental Hg contamination.
Wawan Budianta, Arifudin Idrus, Fahmi Hakim, Augustus C. Resurrection, Hirofumi Hinode   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Gold Mining and Submarine Tailings Disposal: Review and Case Study

Oceanography, 2012
Environmental impacts associated with submarine tailings disposal (STD) of gold mine wastes vary widely among the relatively few cases studied. The principal contaminants of concern surrounding most gold mines are arsenic, mercury, and cyanide, although ...
Evan Edinger
doaj