Results 41 to 50 of about 6,672,830 (309)
Intracranial pressure monitoring: Gold standard and recent innovations
World Journal of Clinical Cases, 2019 Intracranial pressure monitoring (ICP) is based on the doctrine proposed by Monroe and Kellie centuries ago. With the advancement of technology and science, various invasive and non-invasive modalities of monitoring ICP continue to be developed. An ideal
D. Nag, S. Sahu, A. Swain, Shashi Kant
semanticscholar +1 more source
Development of a Lateral Flow Assay for the Detection of the Hepatitis C Virus Core Antigen
PharmaceuticalsBackground: Hepatitis C virus (HCV) infection remains a global health challenge, with millions of people affected annually. Current diagnostic methods, reliant on antibody screening and viral RNA detection, are complex, costly, and often inaccessible ...
Erick Joan Vidal-Alcántara +7 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objective: To determine the diagnostic accuracy of magnetic resonance imaging in diagnosing bone tumors keeping histopathological as correlation gold standard. Study Design: Descriptive cross-sectional study.
Ambreen Farooq +3 more
doaj +1 more source
PLoS ONE, 2019 Objective To systematically review methods developed and employed to evaluate the diagnostic accuracy of medical test when there is a missing or no gold standard.
Chinyereugo M Umemneku Chikere +4 more
semanticscholar +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Why Cognitive Behavioral Therapy Is the Current Gold Standard of Psychotherapy
Frontiers in Psychiatry, 2018 1 Department of Clinical Psychology and Psychotherapy, International Institute for Advanced Study in Psychotherapy and Applied Mental Health at Babes-Bolyai University, Cluj-Napoca, Romania, 2 Department of Population Health Sciences and Policy at Icahn ...
D. David, I. Cristea, S. Hofmann
semanticscholar +1 more source
A Gold Standard for Emotion Annotation in Stack Overflow [PDF]
IEEE Working Conference on Mining Software Repositories, 2018 Software developers experience and share a wide range of emotions throughout a rich ecosystem of communication channels. A recent trend that has emerged in empirical software engineering studies is leveraging sentiment analysis of developers ...
Nicole Novielli +2 more
semanticscholar +1 more source