Results 121 to 130 of about 956,222 (367)
Proceedings of the National Academy of Sciences of the United States of America, 2012 Precisely arranged cytoarchitectures such as layers and nuclei depend on neuronal migration, of which many in vitro studies have revealed the mode and underlying mechanisms. However, how neuronal migration is achieved in vivo remains unknown.
Mitsutoshi Yanagida +4 more
semanticscholar +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
On the idiosome, golgi apparatus, and acrosome in the male germ cells
, 1922 ed by Robert Hall Bowen, author. Columbia University, New York. On the iodiosome, Golgi apparatus, and acrosome in the male germ cells. An attempt has been made to synthesize the results of recent investigations on the relation of the Golgi apparatus and
R. H. Bowen
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Traffic : the International Journal of Intracellular Transport, 2012 The Golgi apparatus is an organelle that has been extensively studied in the model eukaryote, yeast. Its morphology varies among yeast species; the Golgi exists as a system of dispersed cisternae in the case of the budding yeast Saccharomyces cerevisiae,
Yasuyuki Suda, A. Nakano
semanticscholar +1 more source
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Chemistry &Biodiversity, EarlyView.Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang +8 more
wiley +1 more source
Deciphering the sub-Golgi localization of glycosyltransferases via 3D super-resolution imaging
Cell Structure and FunctionThe Golgi apparatus, a crucial organelle involved in protein processing, including glycosylation, exhibits complex sub-structures, i.e., cis-, medial, and trans-cisternae.
Hirokazu Yagi +11 more
doaj +1 more source
Parametric FEM for Shape Optimization applied to Golgi Stack [PDF]
arXiv, 2019 The thesis is about an application of the shape optimization to the morphological evolution of Golgi stack. Golgi stack consists of multiple layers of cisternae. It is an organelle in the biological cells. Inspired by the Helfrich Model \cite{Helfrich}, which is a model for vesicles typically applied to biological cells, a new model specially designed ...
arxiv
ChemBioChem, EarlyView.This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann +2 more
wiley +1 more source
Neural Regeneration Research, 2015 The regulatory mechanisms of cytoplasmic Ca 2+ after myocardial infarction-induced Ca 2+ overload involve secretory pathway Ca 2+ -ATPase 1 and the Golgi apparatus and are well understood.
Li-hua Li, Xiang-rong Tian, Zhi-ping Hu
doaj +1 more source
ChemBioChem, Accepted Article.Proteoglycans (PGs) play roles in many important biological events including growth factor signaling, wound repair, blood coagulation, brain development, and neural stem cell migration. As the glycosaminoglycan chain of PGs is attached to the core protein through a tetrasaccharide linkage region, it is important to decipher the intricate control of the
Po-han Lin, Xuefei Huang
wiley +1 more source