Results 151 to 160 of about 957,365 (341)

Deciphering structural complexity of brain, joint, and muscle tissues using Fourier ptychographic scattered light microscopy

open access: yesVIEW, EarlyView.
This study introduces Fourier ptychographic scattered light microscopy (FP‐SLM). It combines Fourier ptychographic microscopy (FPM), which images large fields of view with high resolution, and computational scattered light imaging (ComSLI), which visualizes densely interwoven fibers.
Simon E. van Staalduine   +3 more
wiley   +1 more source

Seeing the Unseen: Structured Illumination Microscopy for Organelles Dynamics

open access: yesVIEW, EarlyView.
Abstract Super‐resolution microscopy (SRM) has revolutionized the field of biological imaging by surpassing the diffraction limit of light and rendering us the ability to visualize cellular structures and processes at unprecedented resolution. This powerful technique enables the observation of nanoscale details, thereby providing insights into ...
Adrian Tan   +4 more
wiley   +1 more source

Cell‐Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis

open access: yesAging Cell, EarlyView.
We have validated the selective upregulation of LAMP1 in SEN in culture, and the percentage of Lamp1+ cells increases in various tissues with age, as well as in fibrotic lungs following BLM instillation. The RNA‐Sequencing analysis of the Lamp1‐enriched populations confirmed the enrichment of senescence‐related genes.
Gabriel Meca‐Laguna   +8 more
wiley   +1 more source

Golgi apparatus self-organizes into the characteristic shape via postmitotic reassembly dynamics

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
M. Tachikawa, A. Mochizuki
semanticscholar   +1 more source

Senescent Microglia Mediate Neuroinflammation‐Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1

open access: yesAging Cell, EarlyView.
In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu   +8 more
wiley   +1 more source

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