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Transformable Helical Self-Assembly for Cancerous Golgi Apparatus Disruption.

Nano letters (Print), 2021
Golgi apparatus is a major subcellular organelle responsible for drug resistance. Golgi apparatus-targeted nanomechanical disruption provides an attractive approach for killing cancer cells by multimodal mechanism and avoiding drug resistance.
R. Li   +12 more
semanticscholar   +1 more source

Subcompartmentalizing the Golgi apparatus

Current Opinion in Cell Biology, 2005
The subcompartmentalized structure of the Golgi apparatus contributes to efficient glycosylation in the secretory pathway. Subcompartmentalization driven by maturation relies primarily on constant and accurate vesicle-mediated local recycling of Golgi residents.
Manojkumar A. Puthenveedu   +1 more
openaire   +3 more sources

Golgi Apparatus Polarity Indicates Depression-Like Behaviors of Mice Using in Vivo Fluorescence Imaging.

Analytical Chemistry, 2019
Depression is associated with decreased expression of brain-derived neurotrophic factor (BDNF) which assembled in Golgi apparatus. The changes might be closely related to variation in Golgi apparatus polarity.
Ping Li   +7 more
semanticscholar   +1 more source

Calcium in the Golgi apparatus

Cell Calcium, 2007
The secretory-pathway Ca2+-ATPases (SPCAs) represent a recently recognized family of phosphorylation-type ATPases that supply the lumen of the Golgi apparatus with Ca2+ and Mn2+ needed for the normal functioning of this structure. Mutations of the human SPCA1 gene (ATP2C1) cause Hailey-Hailey disease, an autosomal dominant skin disorder in which ...
Jo Vanoevelen   +4 more
openaire   +3 more sources

The organisation of the Golgi apparatus

Current Opinion in Cell Biology, 1998
The past year has seen considerable progress in understanding the mechanism of COPI (coatomer protein I) vesicle docking and SNARE (soluble NSF attachment protein receptor) mediated fusion, the mechanism of cisternal growth and stacking and the regulation of Golgi architecture.
Graham Warren, Vivek Malhotra
openaire   +3 more sources

The Discovery of the Golgi Apparatus

Journal of the History of the Neurosciences, 1999
The existence of the cell organelle which is now known as Golgi apparatus or Golgi complex, or simply as 'the Golgi", was first reported by Camillo Golgi in 1898, when he described in nerve cells an 'internal reticular apparatus' impregnated by a variant of his chromoargentic staining.
openaire   +3 more sources

Camillo Golgi and the discovery of the Golgi apparatus

Histochemistry and Cell Biology, 1998
Camillo Golgi (1843-1926) was born at Corteno, near Brescia, in northern Italy. After graduating in Medicine at the ancient University of Pavia, the former seat of great scientists and naturalists, Golgi continued a long-standing Italian tradition by studying the histology of the nervous system.
openaire   +5 more sources

Endocytic routes to the Golgi apparatus [PDF]

open access: possibleHistochemistry and Cell Biology, 1998
The endocytic routes of labelled lectins as well as cationic ferritin were studied in cells with a regulated secretion, i.e. pancreatic beta cells, and in constitutively secreting cells, i.e. fibroblasts and HepG2 hepatoma cells, paying particular attention to routes into the Golgi apparatus. Considerable amounts of internalised molecules were taken up
Adolf Ellinger   +5 more
openaire   +2 more sources

The Golgi Apparatus

2007
The Golgi apparatus is a membrane-bounded organelle comprised of polarized stacks of cisternae and is required for trafficking of proteins and lipids within all eukaryotic cells. The Golgi, which is positioned centrally in the transport route between the endoplasmic reticulum (ER) and plasma membrane, is an organelle whose size, composition and ...
Nihal Alton-Bonnet   +1 more
openaire   +2 more sources

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