Results 241 to 250 of about 50,115 (352)

Spectrum of Hypogonadism and Its Management in Adolescents With Prader‐Willi Syndrome: A Retrospective Cohort Study Over 35 Years

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen   +2 more
wiley   +1 more source

Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insights. [PDF]

open access: yesHum Reprod Update
Lakshmipathi M   +9 more
europepmc   +1 more source

The Role of Inhibin on Pituitary FSH Secretion and Maturation of Pituitary-Gonadal Axis in Immature Female Rats.

open access: bronze, 1993
Takao Fukaya   +6 more
openalex   +2 more sources

Exploring the Impact of RNU4‐2 Defects on Neurodevelopmental Disorders in a Korean Population

open access: yesClinical Genetics, EarlyView.
Among 15 450 Korean individuals, noncoding RNU4‐2 variants, primarily the recurrent de novo n.64_65insT, make up 0.72% of neurodevelopmental disorders. Modeling and RNA‐seq suggest U4/U6 disruption and abnormal 5′ splice‐site selection, supporting routine use of WGS analysis for reanalyzing unresolved cases. ABSTRACT Neurodevelopmental disorders (NDDs)
Juhyeon Hong   +20 more
wiley   +1 more source

Microplastic Impacts on Seafood: A Global Synthesis of Experimental Findings

open access: yesFish and Fisheries, EarlyView.
ABSTRACT Plastic pollution is a growing global concern, with plastic and microplastic particles now widespread in aquatic environments. Microplastics are frequently ingested by marine organisms, including commercially important seafood species. Ingestion can lead to a range of biological effects, influenced by the size, type and quantity of plastic, as
Nina Wootton   +4 more
wiley   +1 more source

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