Results 101 to 110 of about 20,213 (210)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Endocrine hierarchy in female teleost reproduction: From the HPG core to contextual modulators

Aquaculture Reports
Female fish reproduction is governed by a tightly controlled endocrine network that ensures healthy gamete formation and species continuation. The hypothalamic-pituitary-gonadal (HPG) axis, with its core hormones (GnRH, FSH, LH, and steroid hormones ...
Lanying Yang, You Wu, Wenjing Tao, Minghui Li, Linyan Zhou, Deshou Wang   +5 more
doaj   +1 more source

Better 10‐Year Cerebrovascular Outcome After Transplant Than on Standard‐Care in Sickle Cell Anemia: DREPAGREFFE Trial

American Journal of Hematology, Volume 101, Issue 8, Page 1799-1817, August 2026.
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin, Suzanne Verlhac, Elisabeth Ducros‐Miralles, Cécile Arnaud, Isabelle Genty, Marie Petras, Catherine Paillard, Gonzalo De Luna, Benoit Meunier, Isabelle Thuret, Annie Kamdem, Corinne Pondarré, Giovanna Cannas, Christelle Chantalat‐Auger, Nadia Firah, Sophie Pertuisel, Laure Joseph, Florence Missud, Mariane de Montalembert, Corinne Guitton, Claire Pluchart, Valentine Brousse, Monique Elmaleh, Vincent Gajdos, Emmanuella Leveillé, Ekaterina Belozertseva, Mabel Gaba, Catherine Poirot, Virginie Barraud‐Lange, Philippe Chadebech, France Pirenne, Myriam Bernaudin, Bénédicte Neven, Pierre Frange, Marie Angoso, Karima Yakouben, Bénédicte Bruno, Nathalie Dhédin, Jean‐Hugues Dalle, Regis Peffault Delatour, Camille Jung   +40 more
wiley   +1 more source

Interaction of the Gut Microbiota and the Enteric Nervous System: Implications in Gastrointestinal Disorders Associated With Autism Spectrum Disorder

Autism Research, Volume 19, Issue 8, August 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud, María José Mendoza‐León, Justine Marchix, Alonso Fernandez Tello, Catherine Le Berre Scoul, Ma Cecilia Opazo, Michel Neunlist, Claudia A. Riedel, Martial Caillaud, Hélène Boudin   +9 more
wiley   +1 more source

17, 20 α Dihydroxy Progesterone 07, 20 α DP) Production by Different Tissue in Common Carp (Cyprinus carpio) and Gold Fish (Carasius auratus)

‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 1998
Different tissue (muscle, heart, eye, testis and blood) and sperm from Common carp and Gold fish, in order to evaluate activity of 20α hydroxy steroid Dihydrogenase 20α HSD) enzyme to convert radiactive 17α HP and amount of 0.01, 1 or 10m g of ...
M. Ebrahimi
doaj  

Maternal and Early Developmental Effects of Perinatal Exposure to Therapeutically Relevant Doses of Common Nonsteroidal Anti‐Inflammatory Drugs in Rats

Birth Defects Research, Volume 118, Issue 8, August 2026.
ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used during pregnancy, yet information on their developmental safety during sensitive perinatal windows remains limited. This study evaluated the maternal and early developmental effects of paracetamol/acetaminophen, aspirin, and nimesulide administered at therapeutically ...
Sara Tawany Caetano dos Santos, Reggina Lorena Mellado Castro, Luara Magalhães, Giovanna Ferrari Rosalem, Julia Vitoria Francisco de Aquino, Otávio Galassi Vitale, Livia Trippe Nagaoka, Julia Stein, Beatriz de Matos Manoel, Bárbara Campos Jorge, Arielle Cristina Arena   +10 more
wiley   +1 more source

Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari, Ayat B. Al‐Ghafari, Huda A. Al Doghaither, Ahmed M. S. Hegazy, Ekramy M. Elmorsy, Asmaa Fady Sharif, Zahraa Khalifa Sobh   +6 more
wiley   +1 more source

Corticosterone Under Experimental Manipulation of Nutrition and Parasite Burden in a Wild Rodent System

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 749-758, August 2026.
ABSTRACT Environmental pressures shape survival and life‐history dynamics partly by triggering the release of glucocorticoids, whose short‐term benefits but long‐term costs make it essential to understand what drives their levels. Here, we used an experimental manipulation of two environmental stressors—food availability and parasite burden—to directly
Sarah E. Wolf, Olga Dłużniewska, Simon A. Babayan, Amy B. Pedersen, Tom J. Little   +4 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, Volume 40, Issue 8, Page 4880-4897, August 2026.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Metabolic Reprogramming of Brain Microglia: Implications for Aging and Aging‐Associated Neurodegenerative Diseases

Aging Cell, Volume 25, Issue 8, August 2026.
Microglia, the brain's resident macrophages, undergo metabolic reprogramming during aging, which impacts brain health and neurodegenerative disease risk. Understanding mechanisms of microglial metabolic regulation is key to the development of therapeutic strategies to promote homeostasis and mitigate harmful neuroinflammatory processes that contribute ...
Seokjo Kang, Helen S. Goodridge
wiley   +1 more source