Role of Gonadal Steroid Hormones in the Eye: Therapeutic Implications [PDF]
Gonadal steroid hormones are critical regulatory substances involved in various developmental and physiological processes from fetal development through adulthood. These hormones, derived from cholesterol, are synthesized primarily by the gonads, adrenal
Javier Valero-Ochando +4 more
doaj +7 more sources
Impact of sex in the prevalence and progression of glioblastomas: the role of gonadal steroid hormones [PDF]
Background As in other types of cancers, sex is an essential factor in the origin and progression of glioblastomas. Research in the field of endocrinology and cancer suggests that gonadal steroid hormones play an important role in the progression and ...
Claudia Bello-Alvarez +1 more
doaj +5 more sources
Gonadal steroid hormones and the hypothalamo-pituitary-adrenal axis. [PDF]
The hypothalamo-pituitary-adrenal (HPA) axis represents a complex neuroendocrine feedback loop controlling the secretion of adrenal glucocorticoid hormones. Central to its function is the paraventricular nucleus of the hypothalamus (PVN) where neurons expressing corticotropin releasing factor reside.
Handa RJ, Weiser MJ.
europepmc +7 more sources
Neurosteroid Metabolites of Gonadal Steroid Hormones in Neuroprotection: Implications for Sex Differences in Neurodegenerative Disease [PDF]
Gonadal steroid hormones are neurotrophic and neuroprotective. These effects are modulated by local metabolism of the hormones within the brain. Such control is necessary to maintain normal function, as several signaling pathways that are activated by ...
Ari Loren Mendell, Neil James MacLusky
doaj +3 more sources
The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development. [PDF]
Schulz KM, Sisk CL.
europepmc +4 more sources
Mechanisms of Immune Tolerance and Inflammation via Gonadal Steroid Hormones in Preterm Birth [PDF]
. In 2019, preterm births (PTB) accounted for approximately 0.66 million deaths globally. PTB is also associated with a significantly higher risk of mortality and long-term complications for newborns.
Yang Pan +8 more
doaj +2 more sources
Modulation of appetite by gonadal steroid hormones [PDF]
Several sex differences in eating, their control by gonadal steroid hormones and their peripheral and central mediating mechanisms are reviewed. Adult female rats and mice as well as women eat less during the peri-ovulatory phase of the ovarian cycle (estrus in rats and mice) than other phases, an effect under the control of cyclic changes in estradiol
Lori, Asarian, Nori, Geary
openaire +3 more sources
Temporal organization of gonadal and adrenal steroid fluctuations in male mice [PDF]
Longitudinal arterial sampling combined with LC–MS/MS profiling was used to define the temporal organization of circulating steroid hormones in adult male mice.
M Chase Kettering +8 more
doaj +2 more sources
Transcriptomic and metabolomic analysis of metabolite changes and regulatory mechanisms associated with gonadal degeneration in yellow oil crab (Scylla paramamosain) [PDF]
Background The yellow oil crab is a highly valuable aquatic species, with the accumulation of nutritional and flavor compounds closely linked to the degree of gonadal degeneration. However, the molecular mechanisms of gonadal degeneration remain unclear.
Biwei Wu +4 more
doaj +2 more sources
Effect of gonadal steroid hormones on formalin‐induced temporomandibular joint inflammation [PDF]
AbstractWe have recently demonstrated that gonadal steroid hormones decrease formalin‐induced temporomandibular joint nociception in rats. Given that the attenuation of inflammation is a potential mechanism underlying this antinociceptive effect, we evaluated the effect of gonadal steroid hormones on formalin‐induced temporomandibular joint ...
K E, Torres-Chávez +6 more
openaire +3 more sources

