Results 1 to 10 of about 1,290 (126)

Bilateral Gonadoblastoma in a 12‐Year‐Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case [PDF]

Clinical Case Reports
This case of a 12‐year‐old patient who developed bilateral gonadoblastoma 4 years after treatment for Wilms tumor highlights the importance of rigorous, risk‐adapted long‐term surveillance and careful evaluation of incidental gonadal findings, even in ...
Ahmed Quraish, Hasan Khouli, Yousef Daraghmeh, Sultan Mosleh, Samer Bustame   +4 more
doaj   +3 more sources

Co‐Occurrence of Ovarian Dysgerminoma‐Inducing Gonadoblastoma and Two Distinct Mammary Carcinomas in a Dog: A Case Report and Review of the Literature [PDF]

Veterinary Medicine and Science
Gonadoblastoma (GB) is an extremely rare mixed gonadal neoplasm, encountered in animals as well as humans. The tumour is typically reported in dysgenetic gonads of those suffering from disorders of sex development and bearing the Y chromosome.
Diba Golchin, Farhang Sasani, Saeed Farzad‐Mohajeri, Mohsen Tovhidifar, Iradj Ashrafi Tamai   +4 more
doaj   +3 more sources

Advanced-Stage Gonadal Dysgerminoma in a Patient With a Previous Diagnosis of Familial Swyer Syndrome: A Very Rare Genetic Entity. [PDF]

Case Rep Med
Introduction Swyer syndrome is a genetic abnormality characterized by a 46,XY karyotype in a phenotypically female individual. Affected individuals typically have average or tall stature, unambiguous genitalia at birth, the presence of Müllerian structures, and bilateral streak gonads.
Oğlak SC, Söğütçü N, Akgöl S, Adıgüzel Ö, Ateş Eminoğlu HE, Güzel G, Balcı V, Acar E, Acar A, Bozan F.   +9 more
europepmc   +2 more sources

Stage IIIC Bilateral Dysgerminoma in a 16-Year-Old Phenotypic Female With 46,XY Complete Gonadal Dysgenesis and Primary Amenorrhea: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Dysgerminoma, the most common malignant ovarian germ cell tumor, has a significantly increased incidence in individuals with 46,XY complete gonadal dysgenesis (Swyer syndrome). However, primary amenorrhea is the hallmark presentation of Swyer syndrome in adolescence.
Vasef M, Afshar Moghaddam N, Raoufi M, Iranipour M, Moghadami S.   +4 more
europepmc   +2 more sources

Balancing oncologic risk and fertility potential: a single-center study on Turner syndrome patients with Y chromosome material [PDF]

Frontiers in Endocrinology
IntroductionTurner Syndrome (TS) is a chromosomal disorder characterized by partial or complete monosomy of the X chromosome. Approximately 5–10% of patients with TS harbor Y chromosome material, which is associated with an increased risk of ...
Xia Shuai, Zhibing Guo, Dongguang Zhang, Hui Huang, Ka Chen, Yu Yang, Qinghua Hu   +6 more
doaj   +2 more sources

Male hermaphroditism with rare malignant transformation of gonadal organs: a case report [PDF]

Discover Oncology
A 27-year-old man was admitted to the hospital after a year of marriage due to infertility. During laparoscopic exploratory surgery, the presence of a retrovesical uterus was clearly observed, and the gonadal organs were visible on both sides.
Zhengyu He, Zhiyuan Li, Mei Chen
doaj   +2 more sources

Gonadoblastoma with Dysgerminoma in a Virilized Adolescent with Karyotype 46,XX: A Case Report and Review of the Literature [PDF]

JCRPE
Gonadoblastoma is a rare gonadal tumor composed of sex cord cells and primitive germ cells. While the majority of gonadoblastomas are found in individuals with 46,XY gonadal dysgenesis, they are also rarely seen in patients with a 46,XX karyotype.
Tugce Kandemir, Esin Karakilic Ozturan, Ozlem Dural, Ayca Dilruba Aslanger, Elif Inan Balci, Aysel Bayram, Semen Onder, Asli Derya Kardelen, Melek Yildiz, Sukran Poyrazoglu, Firdevs Bas, Feyza Darendeliler   +11 more
doaj   +2 more sources

Sertoli cell tumor associated with ovarian sex cord tumor with annular tubules in a patient with 46 XY disorder of sex development and 9p24.3 deletion, case report. [PDF]

J Obstet Gynaecol Res
Abstract We report a rare case involving a 22‐year‐old phenotypically female patient who presented to our care with primary amenorrhea and spontaneous breast development. Hormonal analysis indicated hypergonadotropic hypogonadism, and imaging revealed a hypoplastic uterus and calcified ovaries.
Petrillo T, Battipaglia C, Semprini E, Baldessari C, Pirola M, Calabrese O, Farulla A, Ternelli G, Eccher A, Botticelli L, Genazzani AD.   +10 more
europepmc   +2 more sources

Rare presentations of Swyer syndrome in a 13.5-year-old female; a case report and literature review [PDF]

BMC Pediatrics
Background Swyer syndrome (SS), or 46, XY pure gonadal dysgenesis, is a rare disorder of sex development. It typically presents with primary amenorrhea and an absence of secondary sexual characteristics.
Alireza Sadeghi, Romina Rezaei, Zahra Razavi, Amir Mohammad Salehi, Arash Dehghan   +4 more
doaj   +2 more sources

Ovarian Sex Cord Stromal Tumor With Annular Tubules: A Rare Diagnosis in Young Women. [PDF]

Clin Case Rep
ABSTRACT Ovarian sex cord‐stromal tumor with annular tubules (SCTAT) is a rare neoplasm with distinct clinicopathological features in its sporadic and syndromic forms, the latter commonly associated with Peutz‐Jeghers syndrome. Although imaging may suggest a sex cord‐stromal origin, definitive diagnosis relies on histopathological examination.
Marques P, Vieira T, Ilgenfritz RB, Djokovic D.   +3 more
europepmc   +2 more sources