Results 11 to 20 of about 1,949 (196)

Gonadoblastoma with Dysgerminoma Presenting as Virilizing Disorder in a Young Child with 46, XX Karyotype: A Case Report and Review of the Literature

Case Reports in Endocrinology, 2022
Gonadoblastoma is a neoplasm containing an intimate mixture of germ cells and elements resembling immature granulosa or Sertoli cells. It has been considered as in situ germ cell malignancy that can be associated with malignant components.
Prathamesh Chandrapattan, Amitabh Jena, Rashmi Patnayak, Swayamsidha Mangaraj, Sujata Naik, Saroj Panda   +5 more
doaj   +2 more sources

Prevalence of Y-chromosome sequences and gonadoblastoma in Turner syndrome

Revista Paulista de Pediatria, 2016
Objective: To assess the prevalence of Y-chromosome sequences and gonadoblastoma in patients with Turner syndrome (TS) using molecular techniques. Data source: A literature search was performed in Pubmed, limiting the period of time to the years 2005 ...
Alessandra Bernadete Trovó de Marqui, Roseane Lopes da Silva-Grecco, Marly Aparecida Spadotto Balarin   +2 more
doaj   +2 more sources

Prevalence of c-KIT mutations in gonadoblastoma and dysgerminomas of patients with disorders of sex development (DSD) and ovarian dysgerminomas. [PDF]

PLoS ONE, 2012
Activating c-KIT mutations (exons 11 and 17) are found in 10-40% of testicular seminomas, the majority being missense point mutations (codon 816). Malignant ovarian dysgerminomas represent ~3% of all ovarian cancers in Western countries, resembling ...
Remko Hersmus, Hans Stoop, Gert Jan van de Geijn, Ronak Eini, Katharina Biermann, J Wolter Oosterhuis, Catharina Dhooge, Dominik T Schneider, Isabelle C Meijssen, Winand N M Dinjens, Hendrikus Jan Dubbink, Stenvert L S Drop, Leendert H J Looijenga   +12 more
doaj   +4 more sources

Gonadoblastoma and fertility. [PDF]

Journal of Clinical Pathology, 1992
Most patients with gonadoblastoma have dysgenetic gonads. This rare tumour has been described in three pregnant women. A fourth case in a 26 year old pregnant woman who presented with gonadoblastoma and dysgerminoma, is reported. She had a normal term pregnancy, 46XX chromosomes, normal genitalia, no history of menstrual irregularities and no signs of ...
Y, Erhan, A S, Toprak, N, Ozdemir, B, Tiras   +3 more
openaire   +3 more sources

Canine ovarian gonadoblastoma with dysgerminoma overgrowth: a case study and literature review [PDF]

Journal of Ovarian Research, 2019
Background Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome.
Ana R. Flores, João Lobo, Francisco Nunes, Alexandra Rêma, Paula Lopes, Luís Carvalho, Carla Bartosch, Irina Amorim, Fátima Gärtner   +8 more
doaj   +2 more sources

Dysgerminoma and gonadoblastoma in the course of Swyer syndrome [PDF]

Polish Journal of Pathology, 2017
We present a case of a woman with primary amenorrhea. Ultrasound imaging showed a uterus of normal size but bands of connective tissues at the site of ovaries. A genetic test was done which revealed the XY karyotype. Swyer syndrome was diagnosed.
Tomasz Milewicz, Sandra Mrozińska, Wojciech Szczepański, Magdalena Białas, Marta Kiałka, Katarzyna Doroszewska, Monika Kabzińska-Turek, Andrzej Wojtyś, Artur Ludwin, Łukasz Chmura   +9 more
doaj   +2 more sources

Swyer Syndrome With Gonadoblastoma: A Clinicoradiological Approach

Journal of Human Reproductive Sciences, 2017
Primary amenorrhea is a common diagnostic challenge in the gynecology department, wherein there are numerous causes that need to be approached in a systematic manner.
Arjit Agarwal, Shubhra Agarwal
doaj   +2 more sources

Stage IIIC Bilateral Dysgerminoma in 46,XY Swyer Syndrome: Preventing Malignancy Through Early Endocrine Evaluation of Primary Amenorrhea. [PDF]

Clin Case Rep
Clinical Case Reports, Volume 14, Issue 7, July 2026.
Elendu C, Sidhu AK, Okabekwa OS, Debua AT, Ali AI.   +4 more
europepmc   +2 more sources

Gonadoblastoma Arising in Undifferentiated Gonadal Tissue within Dysgenetic Gonads [PDF]

, 2006
Purpose: The purpose of the study was to define the histological origin of gonadoblastomas, allowing the identification of high-risk patients. Experimental Design: Sixty paraffin-embedded gonadectomy or gonadal biopsy samples of 43 patients with ...
Kula, Krzysztof, Looijenga, L. H. J., Wolffenbuttel, K. P., Cools, Martine, Slowikowska-Hilczer, J., Slowikowska-Hilczer, Jolanta, Cools, M., Bourguignon, Jean-Pierre, Stoop, Hans, Drop, S. L. S., Oosterhuis, J. W., Kersemaekers, A. M. F., Faradz, S. M. H., Wolffenbuttel, Katja P, Stoop, H., Kula, K., Bourguignon, JP, Looijenga, LHJ, Slowikowska-Hilczer, J. (Jolanta), Slowikowska-Hilzcer, J, Kersemaekers, AMF, Stoop, H, Looijenga, L.H.J. (Leendert), Cools, M.B.C.M. (Martine), Cools, MBC, Drop, SLS, Faradz, SMH, Kula, K. (Krzysztof), Wolffenbuttel, K.P. (Katja), Oosterhuis, Wolter, Slowikowska-Hilczer, J, Drop, S.L.S. (Stenvert), Faradz, S, Kula, K, Stoop, J.A. (Hans), Wolffenbuttel, Katja, Kersemaekers, AM, Looijenga, LHJ (Leendert), Kersemaekers, A.M. (Anne-Marie), Wolffenbuttel, KP, Oosterhuis, J.W. (Wolter), Faradz, S.M.H. (Sultana), Oosterhuis, JW, Bourguignon, J.-P. (J.), Drop, Sten, Looijenga, Leendert H. J, Oosterhuis, J. Wolter, Faradz, Sultana M.H., Drop, Stenvert L. S, Kersemaekers, Anne-Marie F.   +49 more
core   +4 more sources

Left ovarian gonadoblastoma with yolk sac tumor in a young woman

Indian Journal of Pathology and Microbiology, 2010
Gonodoblastomas with ovarian germ cell tumors other than dysgerminoma coexists very rarely with yolk sac tumor (YST). Because of this rarity, we report a case of gonadoblastoma with YST.
Gelincik Ibrahim, Ozen Suleyman, Bayram Irfan   +2 more
doaj   +2 more sources