Development of the gonadotropin‐releasing hormone system [PDF]
AbstractThis review summarizes the current understanding of the development of the neuroendocrine gonadotropin‐releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic ...
Duittoz, Anne H.+7 more
openaire +5 more sources
A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion [PDF]
Background Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal function. Luteinizing hormone secretion is regulated both by alterations in gonadotrope responsiveness to hypothalamic gonadotropin releasing hormone and by ...
Musgrove Lois C+4 more
doaj +4 more sources
Gonadotropin-Releasing Hormone [PDF]
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Zvi Naor, Rony Seger
semanticscholar +6 more sources
The Role of Gonadotropin-Releasing Hormone (GnRH) in Endometrial Cancer
Endometrial cancer (EC) is one of the most common gynecological malignancies. Gonadotropin releasing hormone (GnRH) is a decapeptide first described to be secreted by the hypothalamus to regulate pituitary gonadotropin secretion.
Günter Emons, Carsten Gründker
doaj +2 more sources
Gonadotropin-Releasing Hormone Receptors [PDF]
GnRH and its analogs are used extensively for the treatment of hormone-dependent diseases and assisted reproductive techniques. They also have potential as novel contraceptives in men and women. A thorough delineation of the molecular mechanisms involved in ligand binding, receptor activation, and intracellular signal transduction is kernel to ...
Colleen A. Flanagan+6 more
openaire +4 more sources
Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre+3 more
core +18 more sources
Suppression of reproductive function in juvenile rams by a slow-release gonadotropin-releasing hormone implant [PDF]
Background: Regarding animal welfare and reversible suppression of reproduction the need for alternatives to surgical castration like slow-release gonadotropin-releasing hormone implants is increasing.
Luise Prestel+4 more
doaj +1 more source
Invitro fertilization outcome in triggering with GnRH agonist, Hcg or combination of GnRH agonist and Hcg [PDF]
Introduction: Human chorionic gonadotropin for the final maturation of eggs in the In-vitro fertilization cycle was associated with the possibility of a negative effect on endometrial acceptance, fetal quality and ovarian hyper stimulation syndrome ...
Alamtaj Samsami+5 more
doaj +1 more source
Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty [PDF]
Purpose There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare.
Ah Young Cho+3 more
doaj +1 more source
Neuroendocrine control of gonadotropin‐releasing hormone: Pulsatile and surge modes of secretion
The concept that different systems control episodic and surge secretion of gonadotropin‐releasing hormone (GnRH) was well established by the time that GnRH was identified and formed the framework for studies of the physiological roles of GnRH, and later ...
R. Goodman+3 more
semanticscholar +1 more source