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The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH), acting via its receptors (GnRHRs) expressed in pituitary gonadotrophs, represents a critical molecule in control of reproductive functions in all vertebrate species.
Marija M. Janjic +2 more
doaj +1 more source
Genetic regulation of pituitary gland development in human and mouse [PDF]
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Aarskog +321 more
core +2 more sources
OBJECTIVES: Unfavorable predicted adult height and psychosocial inadequacy represent parameters used to guide therapeutic intervention in girls with central precocious puberty. Gonadotropin-releasing hormone analog is the first-line treatment. The aim of
Mateus Cavarzan Lopes +4 more
doaj +1 more source
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core +1 more source
Development of Gonadotropin-Releasing Hormone Secretion and Pituitary Response
Acquisition of a mature pattern of gonadotropin-releasing hormone (GnRH) secretion from the CNS is a hallmark of the pubertal process. Little is known about GnRH release during sexual maturation, but it is assumed to be minimal before later stages of ...
Katarzyna M Glanowska +2 more
semanticscholar +1 more source
Abstract Objective The main objective was to describe women with fibroids who were treated with ultrasound‐guided high intensity focused ultrasound (USgHIFU) at the Chris Hani Baragwanath Academic Hospital (CHBAH) and to evaluate the outcomes at least 6 months after treatment.
Raphaela Setzen +7 more
wiley +1 more source
Résumé Contexte L’objectif de notre étude rétrospective était d’évaluer la survie à 5 ans et le délai de transition du cancer de la prostate hormono-sensible au cancer de la prostate résistant à la castration chez des patients porteurs d’un cancer de la ...
Jumpei Asakawa +8 more
doaj +1 more source
Update on male reproductive endocrinology. [PDF]
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core +1 more source
Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria +5 more
core +1 more source
Aвтоимун тироидит по долга употреба на агонист на гонадотропин- ослободувачки хормон како третман за предвремен централен пубертет – приказ на случај [PDF]
There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors.
Krstevska-Konstantinova, Marina +3 more
core +2 more sources

