Genomic technologies and the diagnosis of 46, XY differences of sex development
Andrology, EarlyView.Abstract Differences/disorders of sex development can be caused by disruptions to the molecular and cellular mechanisms that control development and sex determination of the reproductive organs with 1:100 live births affected. Multiple genes are associated with 46, XY differences/disorders of sex development that can cause varying clinical phenotypes ...
Firman Idris +2 more
wiley +1 more source
Administration of Gonadal Steroids to the Castrated Male Rat Prevents a Decrease in the Release of Gonadotropin-Releasing Hormone from the Incubated Hypothalamus [PDF]
, 1979 Robert S. Rudenstein +3 more
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Andrology, EarlyView.Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas +6 more
wiley +1 more source
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
, 2016 Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core +1 more source
Andrology, EarlyView.Abstract Objective To examine the association between semen parameters, assessed according to World Health Organization (WHO)‐2021 criteria, and paternal body mass index (BMI) and age, with embryological and clinical outcomes in ICSI cycles involving preimplantation genetic testing for aneuploidy (PGT‐A).
Rossella Mazzilli +16 more
wiley +1 more source
Aqueous solution interactions with sex hormone-binding globulin and estradiol: A theoretical investigation [PDF]
arXiv, 2017 Sex hormone-binding globulin (SHBG) is a binding protein that regulates availability of steroids hormones in the plasma. Although best known as steroid carrier, studies have associated SHBG in modulating behavioral aspects related to sexual receptivity.
arxiv
Effect of Synthetic Luteinizing Hormone-Releasing Hormone (LH-RH) on the Release of Gonadotropins in Hypophyso-Gonadal Disorders of Children and Adolescents. V. Agonadism [PDF]
, 1974 J. C. JOB +5 more
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Andrology, EarlyView.Abstract Background Current advances in high‐throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.
Linlin Li +4 more
wiley +1 more source
Postmenopausal Hyperandrogenism in a Patient With an Adrenal Adenoma: How Should We Approach It?
AACE Clinical Case Reports, 2016 : Objective: To report the case of a postmenopausal woman with adrenal adenoma and severe hyperandrogenism due to bilateral ovarian hyperthecosis.Methods: We describe the clinical findings and diagnostic tests used to determine the source of excess ...
Lilian C. Mendoza-Mathison, MD +3 more
doaj
Acute and Chronic Effects of Gonadotropin Releasing Hormone on Reproductive Characteristics of Rams during the Nonbreeding Season1 [PDF]
, 1977 B. D. Schanbacher, D. D. Lunstra
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