Aвтоимун тироидит по долга употреба на агонист на гонадотропин- ослободувачки хормон како третман за предвремен централен пубертет – приказ на случај [PDF]
, 2020 There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors.
Krstevska-Konstantinova, Marina +3 more
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Gonadotropin-Releasing Hormone Receptor
Definitions, 2020 GnRHplays a critical role in regulating mammalian reproductive development andfunction. At the level of the anterior pituitary, GnRH binds to the GnRH receptor (GnRHR) on the cell surface ofpituitary gonadotropes.
E. Norwitz, K. Jeong, W. Chin
semanticscholar +1 more source
Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: Results from a pooled analysis [PDF]
, 2015 Background: Male breast cancer is a rare malignancy. Despite the lack of prospectively generated data from trials in either the adjuvant or metastatic setting, patients are commonly treated with hormone therapies.
AB Miller +37 more
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Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
, 2013 Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
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Regulation of reproduction via tight control of gonadotropin hormone levels. [PDF]
, 2018 Mammalian reproduction is controlled by the hypothalamic-pituitary-gonadal axis. GnRH from the hypothalamus regulates synthesis and secretion of gonadotropins, LH and FSH, which then control steroidogenesis and gametogenesis. In females, serum LH and FSH
Coss, Djurdjica
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Gonadotropin-Releasing Hormone Requirements for Ovulation1 [PDF]
Biology of Reproduction, 1997 This article addresses the role of GnRH in ovulation in the context of two general models of GnRH action--deterministic and permissive. According to the deterministic model, increased GnRH secretion is required to induce the preovulatory LH surge and thus ovulation. The permissive model, in contrast, holds that GnRH secretion need not increase. Rather,
Karsch, F.J. +4 more
openaire +5 more sources
Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
, 2016 Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source
Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]
, 2014 Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong +41 more
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The Gonadotropin-Releasing Hormone Pulse Generator.
Endocrinology, 2018 The pulsatile release of GnRH and LH secretion is essential for fertility in all mammals. Pulses of LH occur approximately every hour in follicular-phase females and every 2 to 3 hours in luteal-phase females and males.
A. Herbison
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background The risk of cardiac dysfunction for patients with prostate cancer undergoing androgen deprivation therapy (ADT) in the real‐world setting remains unclear.
Dong‐Yi Chen +12 more
doaj +1 more source