Results 21 to 30 of about 76,581 (257)

Pregnancy Outcomes of Different Endometrial Preparation in Patients With a History of Cesarean Section

Frontiers in Endocrinology, 2022
ObjectiveTo investigate the efficacies of three cycle regimens in women receiving frozen embryo transfer with a history of cesarean section: natural cycle treatment, hormone replacement therapy and treatment with gonadotropin-releasing hormone agonist ...
Run Xin Gan, Run Xin Gan, Yuan Li, Yuan Li, Juan Song, Quan Wen, Quan Wen, Guang Xiu Lu, Guang Xiu Lu, Ge Lin, Ge Lin, Fei Gong, Fei Gong   +12 more
doaj   +1 more source

Protein and mRNA expression of gonadotropin-releasing hormone receptor in yaks during estrus

Revista Brasileira de Zootecnia, 2018
To demonstrate the role of gonadotropin-releasing hormone (GnRH) in yaks (Bos grunniens), we characterized the expression of gonadotropin-releasing hormone receptor (GnRHR) mRNA and protein.
Sheng-dong Huo, Tao-jie Zhang, Ayimuguli Abudureyimu, Jun-lin Liu, Guo-hua Zhang, Zhong-ren Ma   +5 more
doaj   +1 more source

Morning basal luteinizing hormone, a good screening tool for diagnosing central precocious puberty [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Purpose The standard method used to diagnose central precocious puberty (CPP) is the gonadotropin releasing hormone stimulation test (GnRHST). However, this test is inconvenient for children because it is time-consuming and requires multiple samples ...
Dong-Min Lee, In-Hyuk Chung
doaj   +1 more source

Safety, Pharmacokinetic and Pharmacodynamic Evaluation of Teverelix for the Treatment of Hormone-Sensitive Advanced Prostate Cancer: Phase 2 Loading-Dose-Finding Studies

Medicina, 2023
Background and objectives: Teverelix drug product (DP) is a gonadotropin-releasing hormone antagonist in development for the treatment of patients with prostate cancer in whom androgen deprivation therapy is indicated. The aim of this paper is to present
Carol M. MacLean, Albertas Ulys, Feliksas Jankevičius, Žilvinas Saladžinskas, Steve van Os, Finn Larsen   +5 more
doaj   +1 more source

pS6K1 as an efficacy marker of GnRH agonist with premenopausal breast cancer

Endocrine Connections, 2019
Estradiol is a key factor for tumorigenesis and prognosis of hormone receptor-positive breast cancer. Adipocytes are one source of estradiol in patients with breast cancer. Recent studies have shown that phosphorylated ribosomal protein S6 kinase-1 plays
Chan Sub Park, Jihye Choi, Min-Ki Seong, Sung-Eun Hong, Jae-Sung Kim, In-Chul Park, Hyesil Seol, Woo Chul Noh, Hyun-Ah Kim   +8 more
doaj   +1 more source

Profile of Relugolix in the Management of Advanced Hormone-Sensitive Prostate Cancer: Design, Development, and Place in Therapy

Drug Design, Development and Therapy, 2023
Tomoyuki Tatenuma,1,2 Hiroshi Miyamoto1,3 1Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA; 2Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Japan ...
Tatenuma T, Miyamoto H
doaj  

Central precocious puberty secondary to peripheral precocious puberty due to a pineal germ cell tumor: a case and review of literature

BMC Endocrine Disorders, 2023
Background The pineal lesion affecting melatonin is a rare cause of central precocious puberty by decreasing the inhibition of hypothalamic–pituitary–gonadal axis.
Han Chen, Cai-Yan Mo, Li-yong Zhong
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Efficacy of triptorelin pamoate 11.25 mg administered subcutaneously for achieving medical castration levels of testosterone in patients with locally advanced or metastatic prostate cancer

Therapeutic Advances in Urology, 2015
Objectives: Gonadotropin-releasing hormone agonists are widely used as androgen deprivation therapy in many men with locally advanced or metastatic prostate cancer. Gonadotropin-releasing hormone agonists are delivered by intramuscular injection every 1,
Thiery Lebret, Mathieu Rouanne, Oleg Hublarov, Viorel Jinga, Lidiya Petkova, Rumen Kotsev, Ioanel Sinescu, Pascale Dutailly   +7 more
doaj   +1 more source

Investigation the polymorphism of gonadotropin releasing hormone receptor gene in Iraq sheep

The Iraqi Journal of Veterinary Medicine, 2017
In the present study, the investigation includes the estrus activity after synchronization of estrus by using 20 mg impregnated sponges with Medroxy Progesterone Acetate for 12 days with 400 IU I/M injection of pregnant mare serum gonadotropin 24 hrs ...
Hayder Abdul-Kareem Hasan AL-Mutar
doaj   +1 more source