Results 21 to 30 of about 261,543 (347)

Clinical applications of gonadotropin-releasing hormone analogues: a broad impact on reproductive medicine

F&S Reports, 2023
Gonadotropin-releasing hormone (GnRH) is central to the control of the entire hypothalamic-pituitary-gonadal axis. Manipulation of GnRH, in turn, regulates pituitary response and ovarian hormone production.
Farrah L. Saleh, M.D., Hugh S. Taylor, M.D.   +1 more
doaj   +1 more source

A regulator of G Protein signaling, RGS3, inhibits gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone (LH) secretion

BMC Cell Biology, 2001
Background Luteinizing hormone secreted by the anterior pituitary gland regulates gonadal function. Luteinizing hormone secretion is regulated both by alterations in gonadotrope responsiveness to hypothalamic gonadotropin releasing hormone and by ...
Musgrove Lois C, Sellers Jeffrey C, Duck L Wayne, Neill Jimmy D, Kehrl John H   +4 more
doaj   +1 more source

Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: Results from a pooled analysis [PDF]

, 2015
Background: Male breast cancer is a rare malignancy. Despite the lack of prospectively generated data from trials in either the adjuvant or metastatic setting, patients are commonly treated with hormone therapies.
AB Miller, AM Shaaban, BZ Leder, C Bighin, Carla Azzurra Amoreo, Daniele Santini, Domenico Sergi, F Labrie, F Zagouri, F Zagouri, F Zagouri, Franca Belli, GG T’Sjoen, H Eggemann, Isabella Sperduti, J Doyen, J White, JL Hayward, L Lauro Di, L Lauro Di, LA Korde, Laura Pizzuti, Luigi Di Lauro, M Callari, M Lopez, M Lopez, M Maugeri-Saccà, Maddalena Barba, Marcella Mottolese, Marcello Maugeri-Saccà, N Mauras, Patrizia Vici, Ruggero De Maria, SA Burnett-Bowie, SH Giordano, SH Giordano, Valerie Speirs, WF Anderson   +37 more
core   +4 more sources

Induction of final oocyte maturation in Cyprinidae fish by hypothalamic factors: a review

Veterinární Medicína, 2009
Gonadotropin-releasing hormone in Cyprinidae as in other Vertebrates functions as a brain signal which stimulates the secretion of luteinizing hormone from the pituitary gland. Two forms of gonadotropin-releasing hormone have been identified in cyprinids,
P. Podhorec, J. Kouril
doaj   +1 more source

Gonadotropin-releasing hormone agonist contributes to the successful implementation of in vitro fertilization in a patient with cervical endometriosis: a case report

AJOG Global Reports, 2023
This is a case report of a nulliparous young woman who suffered from prolonged menstruation and infertility for 1 year. Magnetic resonance imaging and a transvaginal ultrasound examination revealed cervical endometriosis.
Turui Yang, MD, Jieling Feng, MD, Lu Luo, PhD, Dan Zhang, PhD, Minghui Chen, PhD   +4 more
doaj   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]

, 2014
Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong, Armstrong, Armstrong, Armstrong, Barrell, Belchetz, Bliss, Bliss, Burger, Bédécarrats, Cardenas, Caunt, Caunt, Caunt, Chuderland, Ciccone, Clayton, Crowley, Cullen, Durham, Ferris, Haisenleder, Haisenleder, Kanasaki, Lawson, Markevich, Marshall, Marshall, Millar, Moenter, Naor, O'Byrne, Padmanabhan, Purvis, Reiss, Savoy-Moore, Shupnik, Sisk, Tomida, Tsaneva-Atanasova, Tsutsumi, Williams   +41 more
core   +2 more sources

Gonadotropin-Releasing Hormone Receptor

Definitions, 2020
GnRHplays a critical role in regulating mammalian reproductive development andfunction. At the level of the anterior pituitary, GnRH binds to the GnRH receptor (GnRHR) on the cell surface ofpituitary gonadotropes.
E. Norwitz, K. Jeong, W. Chin
semanticscholar   +1 more source

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica, Jonak, Carrie R, Kauffman, Alexander S, Xie, Changchuan   +3 more
core   +1 more source

Gonadotropin-releasing hormone antagonists [PDF]

Current Opinion in Pharmacology, 2003
Hypothalamic gonadotropin-releasing hormone (GnRH) is a decapeptide that stimulates pituitary synthesis and secretion of gonadotropins and, therefore, gonadal hormones. GnRH antagonists, of which thousands have been formulated, inhibit the hormone from binding to its receptor, inducing a pharmacological hypophysectomy.
openaire   +2 more sources