Expression and Role of Gonadotropin-Releasing Hormone 2 and Its Receptor in Mammals
Gonadotropin-releasing hormone 1 (GnRH1) and its receptor (GnRHR1) drive mammalian reproduction via regulation of the gonadotropins. Yet, a second form of GnRH (GnRH2) and its receptor (GnRHR2) also exist in mammals.
Amy T. Desaulniers +3 more
doaj +1 more source
Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]
Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B. +3 more
core +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
The role of the chicken gonadotropin-releasing hormone receptor C-terminal tail in expression and coupling [PDF]
The role of the carboxy terminal tail of the chicken gonadotropin-releasing hormone receptor was determined by testing the activity of a series of chicken gonadotropinreleasing hormone receptors with progressive deletions in their carboxyl terminus.
Lopes, John
core +1 more source
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]
There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
core +2 more sources
Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika +6 more
wiley +1 more source
A model-based analysis to guide gonadotropin-releasing hormone receptor antagonist use for management of endometriosis. [PDF]
Pohl O +5 more
europepmc +1 more source
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang +5 more
wiley +1 more source
The novel oral gonadotropin-releasing hormone receptor antagonist relugolix is a new option for controlled ovarian stimulation cycles. [PDF]
Komiya S +5 more
europepmc +1 more source
Site‐level differences in population growth (λ) and phenotype frequencies. Mountain silhouettes represent the three study sites. Morph relative abundances are shown in the colored vertical bar. Point estimates and confidence intervals of λ for each site are displayed below, with the dashed line marking the threshold for demographic stability (λ = 1 ...
Brasil Canales‐Gordillo +4 more
wiley +1 more source

