Assessment of Clinical Drug-Drug Interactions of Elagolix, a Gonadotropin-Releasing Hormone Receptor Antagonist. [PDF]
J Clin Pharmacol, 2020 Polepally AR +8 more
europepmc +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell +3 more
wiley +1 more source
Comparative Performance of Kenyan and Imported Artemia in Early Larval Rearing of Clarias gariepinus
Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.ABSTRACT Successful larval rearing of fish depends largely on live feed availability, during the critical first‐feeding stage. In Kenya, hatcheries commonly use phytoplankton or imported Artemia cysts as starter feeds, although locally produced Artemia is available. Hatchery operators' reports on low larval survival when using imported Artemia prompted
Morine M. Ngarari +9 more
wiley +1 more source
Genomic and Non-Genomic cross talk between the Gonadotropin- releasing hormone receptor and glucocorticoid receptor signalling pathways [PDF]
, 2009 Kotitschke, Andrea
core +1 more source
Rescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity. [PDF]
Sci Rep, 2020 Smith E +6 more
europepmc +1 more source
Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang +9 more
wiley +1 more source
Clinical Pharmacology of Elagolix: An Oral Gonadotropin-Releasing Hormone Receptor Antagonist for Endometriosis. [PDF]
Clin Pharmacokinet, 2020 Shebley M +8 more
europepmc +1 more source
Fertility‐Sparing Treatment of Endometrial Cancer: Survey of Australian Practice
Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 5, October 2026.ABSTRACT Background Endometrial cancer is the most common gynaecological malignancy in Australia. Patients diagnosed in their reproductive window may desire a fertility‐sparing approach, opposed to standard surgical care. International guidelines on fertility‐sparing management exist; however, these highlight the lack of high‐level evidence to support ...
Harrison Odgers, Rhonda Farrell
wiley +1 more source
Polymorphism of the Gonadotropin-Releasing Hormone Receptor Gene and Its Association With Production Traits in Isfahani Native Hens. [PDF]
Vet Med SciKheiri F +4 more
europepmc +1 more source