Results 171 to 180 of about 1,676,067 (279)

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul   +3 more
wiley   +1 more source

Multi‐Mechanistic Effects of Xylopia aethiopica Fruits on Uterine Fibroids: Insights From In Vivo and In Silico Evidence

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Xylopia aethiopica fruit extract modulates progesterone and estradiol levels in monosodium glutamate‐induced uterine fibroid models. In silico analyses reveal strong binding of its phytochemicals to progesterone, estrogen, VEGFR2, and TGF‐β receptors, indicating multi‐target anti‐fibroid actions involving hormonal regulation, anti‐angiogenesis, and ...
Adedokun Oluwasegun, Ume Ogochukwu, Akinsola Olubiyi, Agada Emmanuel, Adebiyi Omowumi, Idogho Eseoghena, Adedokun Folake, Adekunle Temilade   +7 more
wiley   +1 more source

46 XX Ovotesticular Disorder of Sex Development with Gonadotropin-Releasing Hormone Receptor, Autosomal Recessive Heterozygous Missense Mutation and Autosomal Dominant Heterozygous Missense Mutation of the <i>PROKR2</i> Gene: A Case Report. [PDF]

Glob Med Genet
Peranzoni F, De Castro R, Merlini E, Nguyen YL.   +3 more
europepmc   +1 more source

Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer. [PDF]

Front Oncol, 2020
Liu Q, Zhou X, Feng W, Pu T, Li X, Li F, Kang Y, Zhang X, Xu C.   +8 more
europepmc   +1 more source

Melatonin Regulates Growth‐Arrest and DNA‐Damage Genes GADD153, GADD45g and GADD34 in Experimental Varicocele

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT This study aimed to reveal the relationship between experimental varicocele and melatonin levels. Forty adult Wistar albino rats were used in this study. Control (C), Melatonin (M), Varicocele (V), Varicocele+Melatonin (V + M) were planned. Varicocele was created on the first day of the experiment by opening the abdominal area, narrowing the ...
Esra Önal, Numan Baydilli, Derya Karabulut   +2 more
wiley   +1 more source

Fewer Injections and Lower Drug Costs With Long‐Acting GnRH Depot Formulations: A Nationwide Analysis of 2.3 Million Patient‐Years in Japan

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Androgen deprivation therapy (ADT) is the base of treatment for prostate cancer, and gonadotropin‐releasing hormone (GnRH) drugs are given as depot injections. Long‐acting formulations may reduce the number of injections and the drug cost, but this impact has not been quantified in real practice.
Takashi Kawahara, Akihito Hashizume, Masanobu Yamazaki, Daiji Takamoto, Teppei Takeshima, Hiroji Uemura, Kazuhide Makiyama, Jun‐ichi Teranishi   +7 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications

Food Frontiers, Volume 7, Issue 5, September 2026.
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley   +1 more source

Photo‐affinity inactivation of gonadotropin releasing hormone receptors

FEBS Letters, 1981
openaire   +2 more sources

TSG From Polygonum multiflorum Thunb. Attenuates Experimental Premature Ovarian Insufficiency in Association With Reduced ZBP1/PANoptosis Signaling

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study shows that TSG, the major bioactive constituent of Polygonum multiflorum Thunb., ameliorates POI in association with suppression of ZBP1‐driven PANoptosis. In a POI rat model, TSG restored estrous cyclicity, improved hormone profiles, and preserved follicular reserve.
Jinhong Li, Tiao Xie, Chang Lin, Danhong Peng, Qin Shi, Can Zhu   +5 more
wiley   +1 more source