Results 41 to 50 of about 1,676,067 (279)

Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]

, 2004
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Guimond, S, Bouloux, PM, Turnbull, Jeremy, Turnbull, J, Hu, Youli, Kim, SH, Kim, Soo-Hyun, Schofield, Jonathan, Winyard, P, Winyard, Paul, Vannelli, GB, Bouloux, Pierre-Marc, Gonzalez-Martinez, D, Hu, YL, Schofield, J, Vannelli, Gabriella Barbara, González-Martínez, David, Guimond, Scott   +17 more
core   +1 more source

Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites [PDF]

Fertility and Sterility, 2016
To investigate whether gonadotropin-releasing hormone (GnRH) and GnRH receptor (GnRHR) are expressed at tubal ectopic pregnancy sites, and to study the potential role of GnRH signaling in regulating immortalized human trophoblast cell viability.Immunohistochemical and experimental studies.Academic research laboratory.Fallopian tube implantation sites ...
Peng, Bo, Klausen, Christian, Campbell, Lisa, Leung, Peter C K, Horne, Andrew W, Bedaiwy, Mohamed A   +5 more
openaire   +3 more sources

At the transition from invertebrates to vertebrates a novel GnRH-like peptide emerges in amphioxus [PDF]

, 2014
This work was supported by a grant from the Canadian Natural Sciences and Engineering Council (NSERC).Gonadotropin-releasing hormone (GnRH) is a critical reproductive regulator in vertebrates.
Roch, Graeme, Sherwood, Nancy, Tello, Javier   +2 more
core   +1 more source

Putative Role of the Kisspeptin/Kiss1R System in Promoting Hypothalamic GnRH Release, Pubertal Maturation, and Regulation of Ovulation Considering the Central Reproductive Axis

Fertility & Reproduction, 2022
Kisspeptin is a class of neuropeptides that are the product of the Kiss1 gene. These neuropeptides play an important role in maintaining gonadotropin-releasing hormone (GnRH) levels and their release through hypothalamic neurons.
Haroon Latif Khan, Shahzad Bhatti, Zirva Sehole, Hooria Younas, Sammar Nathaniel, Sana Abbas, Celal Kaloglu, Rachel Ziders, Aysegul Yildiz, Ahmed M. Isa   +9 more
doaj   +1 more source

Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells : Implications for luteolysis [PDF]

, 2009
The human LH receptor (LHR) plays a key role in luteal function and the establishment of pregnancy through its interaction with the gonadotropins LH and human chorionic gonadotropin.
Dickinson, Rachel E, Myers, Michelle, Duncan, W Colin, Stewart, Alan J., Millar, Robert P   +4 more
core   +1 more source

Invertebrate Gonadotropin-Releasing Hormone-Related Peptides and Their Receptors: An Update

Frontiers in Endocrinology, 2017
Gonadotropin-releasing hormones (GnRHs) play pivotal roles in reproductive functions via the hypothalamus, pituitary, and gonad axis, namely, HPG axis in vertebrates.
Tsubasa Sakai, Akira Shiraishi, Tsuyoshi Kawada, Shin Matsubara, Masato Aoyama, Honoo Satake   +5 more
doaj   +1 more source

Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland

International Journal of Endocrinology, 2022
Hyperandrogenism causes dysfunction of the hypothalamic–pituitary–gonadal (HPG) axis in reproductive women. In this study, we examined the effects of dihydrotestosterone (DHT) on characteristic changes in rat anterior pituitary gland samples.
Haruhiko Kanasaki, Tuvshintugs Tumurbaatar, Zhouma Cairang, Zolzaya Tumurgan, Aki Oride, Hiroe Okada, Satoru Kyo   +6 more
doaj   +1 more source

A study of association between genetic markers in candidate genes and reproductive traits in one generation of a commercial broiler breeder hen population [PDF]

, 2004
Markers of alleles for three physiological candidate genes for reproductive traits, growth hormone (GHR), gonadotropin-releasing hormone receptor (GNRHR) and neuropeptide Y (NPY) were assessed for the association with the total egg production, number of ...
I C Dunn, A Morris, M N Romanov, Dunn, I C, Morris, A, Y W Miao, Romanov, Michael N, Wilson, P W, Waddington, David, D Waddington, Miao, Yi-Wei, P W Wilson   +11 more
core   +1 more source

Recent Development of Non-Peptide GnRH Antagonists

Molecules, 2017
The decapeptide gonadotropin-releasing hormone, also referred to as luteinizing hormone-releasing hormone with the sequence (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) plays an important role in regulating the reproductive system.
Feng-Ling Tukun, Dag Erlend Olberg, Patrick J. Riss, Ira Haraldsen, Anita Kaass, Jo Klaveness   +5 more
doaj   +1 more source

Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling [PDF]

, 2012
Congenital hypogonadotropic hypogonadism (CHH) is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1) result in CHH when present as compound heterozygous or ...
Newton, Claire, Young, Jacques, Claire L Newton, Millar, Robert, Newton, Claire L., Guiochon-Mantel Anne, Young Jacques, Guiochon-Mantel, Anne, Millar, Robert P., Bouligand, Jerome, Newton Claire L., Millar, Robert P, Tello Javier A., Tello, Javier, Anne Guiochon-Mantel, Newton, Claire L, Tello, Javier A., Millar Robert P., Robert P Millar, Jerome Bouligand, Jacques Young, Bouligand Jerome, Tello, Javier A, Javier A Tello   +23 more
core   +2 more sources