Results 141 to 150 of about 37,897 (220)

The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model

Annals of Neurology, Volume 99, Issue 5, Page 1287-1302, May 2026.
Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins, Philip H. Iffland II, John Page, Rebecca Z. Flessner, Soad M. Elziny, Irina Sbornova, Janice K. Babus, Sophie R. Bruckmeier, Ria Parikh, Merel Verhoeven, James Fasham, Joseph S. Leslie, Richard Caswell, Nishanka Ubeyratna, Olivia Wenger, Ethan M. Scott, John Schreiber, Steffen Syrbe, Annick Klabunde‐Cherwon, Martina Owens, Andrew H. Crosby, Emma L. Baple, Peter B. Crino, the KPTN Consortium, Andrea Seeley, Heather Rocha, Sabine Rudnick, Ulrich Schaatz, Tobias Haack, Eva Schwaibold, Caleb Bupp, Klaas Wierenga, John Schreiber, Thorkild Terkelsen, Sarina Kant, J. C. Herkert, Michael Wright, Boris Keren, Solveig Heide, Pamela Jackson, Pradeep Vasudevan, Helen Stewart, Perrine Charles, Andreas Hahn, Saskia Biskup, Inger‐Lise Mero, Martin Heier, Conny van Ravenswaaij‐Arts, Esther Nibbeling, Stephanie Efthymiou, Erum Afzal, Ian Ellis, Raza Maroofian, Almundher Al‐Maawali, David Coman, Anthony Morosini, Sajjad Biglari, Pooneh Nikuei, Saadet Mercimek‐Andrews, Prab Prabhakar, Raymond Louie, Kameryn Butler, Olivia Wenger, Ethan M. Scott, Andrea Seeley, Heather Rocha, Amber Begtrup, Sabine Rudnik, Ulrich Schatz, Tobias Haack, Eva Schwaibold, Caleb Bupp, Klaas Wierenga, John Schreiber, Thorkild Terkelsen, Sarina Kant, J. C. Herkert, Michael Wright, Boris Keren, Solveig Heide, Pamela Jackson, Pradeep Vasudevan, Helen Stewart, Perrine Charles, Andreas Hahn, Saskia Biskup, Inger‐Lise Mero, Martin Heier, Marijn Stokman, Conny van Ravenswaaij‐Arts, Esther Nibbeling, Stephanie Efthymiou, Erum Afzal, Kristina Zhelcheska, Henry Houlden, Ian Ellis, Reza Maroofian, Gholamreza Shariati, Hamid Galehdari, Almundher Al‐Maawali, Adila Al‐Kindi, Andrew Y. Shuen, Victoria Siu, Annick Klabunde‐Cherwon, Steffen Syrbe   +104 more
wiley   +1 more source

Telecological Collapse: The Inevitability of Climate Breakdown in the Transmedial Podcast Drama Forest 404

Future Humanities, Volume 4, Issue 1, May 2026.
ABSTRACT This paper presents a close‐hearing analysis of Forest 404, a transmedial audio drama that was released to BBC Sounds in 2019. Despite the drama's eco‐dystopian critique of teleological ‘progress’ narratives (that enable and perpetuate the destruction of the natural world), I argue that the series ultimately propagates a sense of inevitability
Matilda Jones
wiley   +1 more source

Epidemiological Features and Temporal Trends of Five Common Sexually Transmitted Infections Excluding HIV, 1990–2021: Findings From the Global Burden of Disease Study

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Sexually transmitted infections (STIs) remain a major global health threat. A comprehensive assessment of their epidemiological features and future trajectories is essential for informing targeted public health policies and achieving international control targets.
Baigong Feng, Liwei Liu, Meizhuo Li, Jing Zhang, Yan Lian, Xiang Du   +5 more
wiley   +1 more source

Acting authentically: Using play to cultivate authentic interrelating in role performance

Journal of Organizational Behavior, Volume 47, Issue 4, Page 527-549, May 2026.
Summary Research is increasingly demonstrating that authenticity and human connection are fundamental and interrelated human needs. However, organizational roles often constrain authenticity and connection in workplace interactions, especially roles that are highly scripted.
Lyndon E. Garrett
wiley   +1 more source

Rapid communications [PDF]

This report describes one case of verified treatment failure of pharyngeal gonorrhoea using ceftriaxone in Sweden. Previous reports described verified treatment failure of urogenital gonorrhoea using the internationally recommended first-line drug ...
D Golparian A Hestner, M Unemo
core  

Contrasted habitat selection among Eurasian curlew populations according to landscape heterogeneity and breeding stage

The Journal of Wildlife Management, Volume 90, Issue 4, May 2026.
This study aimed to quantify the spatio‐temporal use of breeding environments by the Eurasian curlew in 5 contrasting agricultural landscapes. To this end, 64 individuals were tagged with GPS devices to assess their space use according to their breeding stages and define their foraging habitat selection.
Marie Donnez, Emmanuel Joyeux, Frédéric Jiguet, Jean‐Noël Ballot, Jeanne Bienvenut, Alain Chartier, Etienne Debenest, Charlotte Francesiaz, Aurélien Lacondemine, Christophe Lartigau, Yves‐Marie Le Guen, Jacques Maout, Charline Pierrefeu, David Pinaud, Nicolas Terrel, Pierrick Bocher   +15 more
wiley   +1 more source

Assessing the Impact of Female Genital Mutilation/Cutting on Genital Inflammation and Microbiota Among Kenyan Female Sex Workers

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Problem Female genital mutilation/cutting (FGM/C) is harmful to physical, mental, and reproductive health, though the effect of this practice on a woman's HIV susceptibility is poorly understood. Despite the known associations of FGM/C with short‐term vaginal epithelial damage, neither genital inflammation nor the genital microbiome have been ...
James Pollock, Rachel Liu, Elizabeth Rwenji, Evelyne Orobi, Suji Udayakumar, Sanja Huibner, Mary Kung'u, Rhoda Kabuti, Hellen Babu, Maisha Fiti Study Champions, Erastus Irungu, Pauline Ngurukiri, Peter Muthoga, Wendy Adhiambo, Helen A. Weiss, Janet Seeley, Tanya Abramsky, Joshua Kimani, Tara S. Beattie, Rupert Kaul   +19 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

"I would walk through fire to get this vaccine": a mixed-methods study examining attitudes and perceptions of a gonorrhoea vaccine programme among UK sexual health service users. [PDF]

BMJ Public Health
Firth C, Wilkinson S, Martin S, Vanderslott S, Pollard AJ, Pollock KM.   +5 more
europepmc   +1 more source

The Complexity of Expressions of Approval—One Aspect of Relational Practice in Diverse Workplaces

International Journal of Applied Linguistics, Volume 36, Issue 2, Page 1045-1055, May 2026.
ABSTRACT The majority of workplaces in Aotearoa New Zealand typically include team members from diverse cultural backgrounds, and yet an orientation to majority group norms (in this case, Pākehā) still dominates. In this article, we draw on naturally occurring workplace talk in a range of workplaces to explore both dominant group practices and norms ...
Janet Holmes, Bernadette Vine
wiley   +1 more source