Results 121 to 130 of about 2,120 (245)
Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients—case report and comprehensive review of the literature [PDF]
, 2016 core +1 more source
Preneoplasias cutáneas y de mucosa oral [PDF]
, 2018 Este trabajo hace foco sobre aquellas dermatosis que pueden dar origen a tumores. Enfatiza el reconocimiento de las mismas a partir del examen clínico y de los métodos de laboratorio que aseveran ese diagnóstico.
Driban, Nelson E. +2 more
core
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Persistent Fever and Cough in a Patient With Good's Syndrome: A Case Report. [PDF]
Cureus, 2022 Turaes AS +4 more
europepmc +1 more source
What’s Fair – and Why? An Empirical Analysis of Distributive Fairness in the Climate Negotiations [PDF]
, 2016 In the climate negotiations, conceptions of fairness plays an important role. For a climate agreement to be effective and durable, it must be conceived as fair by as many of its parties as possible.
Tørstad, Vegard H.
core +1 more source
First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria
Advanced Science, EarlyView.We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena +5 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang +17 more
wiley +1 more source
Tracing value added in gross exports of the automotive industry : the case of France and Germany
, 2015 Due to the increasing fragmentation of international production chains, traditional export statistics lose their reliability to depict value streams between countries.
Längle, Katharina Birgitta
core
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Achromobacter xylosoxidans/denitrificans Bacteremia in a Patient With Good's Syndrome. [PDF]
Cureus, 2021 Choudhury S +4 more
europepmc +1 more source