Results 1 to 10 of about 14,924 (223)

Management of hypogammaglobulinemia in pediatric patients with refractory lupus nephritis: a focus on belimumab [PDF]

Frontiers in Pediatrics
BackgroundAlthough the use of belimumab in children with lupus nephritis (LN) has increased over the past few years, there are limited data on the safety of belimumab in such patients with hypogammaglobulinemia. There are scarce reports of an association
Yanan Han, Yanjun Yang, Peitong Han, Xiaoying Yuan, Chunzhen Li, Jieyuan Cui   +5 more
doaj   +2 more sources

Improving screening for antibody deficiency using calculated globulin and serum protein electrophoresis [PDF]

Frontiers in Immunology
PurposeAntibody deficiencies, particularly Common Variable Immunodeficiency (CVID), represent a major health concern due to comorbidities linked to delayed diagnosis.
Linda Mokrane, Azzeddine Tahiat, Sihem Taguemount, Hassen Messaoudi, Nadia Boukhenfouf, Abdelbassat Ketfi, Leila Smati, Rachida Boukari, Kamel Djenouhat   +8 more
doaj   +2 more sources

Case report: Persistent hypogammaglobulinemia following hematopoietic stem cell transplantation from a sibling donor with heterozygous RAG1 mutation [PDF]

Frontiers in Immunology
IntroductionHematopoietic stem cell transplantation (HSCT) is a curative treatment for pediatric hematologic and immunologic disorders, with successful immune reconstitution being critical for long-term survival.
Jing Wu, Huifang Wang, Weijie Chen, Zhiming Hong   +3 more
doaj   +2 more sources

Calculated globulin as a surrogate marker for hypogammaglobulinemia: establishing clinical decision limits in a Brazilian population cohort [PDF]

Frontiers in Immunology
IntroductionInborn errors of immunity (formerly primary immunodeficiencies) encompass a group of genetic disorders characterized by defects in innate and/or adaptive immunity.
André L. O. Feodrippe, Gabriela Negritu, Ana C. Guersoni, Cristina M. Kokron, Cristina M. Kokron   +4 more
doaj   +2 more sources

CART CELL THERAPY BLACK SHADOW IN HEMATOLOGICAL DISORDERS : SYSTEMIC REVIEW WITH META-ANALYSIS

Hematology, Transfusion and Cell Therapy, 2022
Aim: To determine the effect of CART therapy on hypogammaglobulinemia and bone marrow aplasia, and to determine the probable medications in management of hypogammaglobulinemia with other associated risk factors and complications.
Ghada EL Gohary
doaj   +1 more source

Fresh-frozen plasma as a low-cost replacement of intravenous immunoglobulin for the treatment of symptomatic hypogammaglobulinemia

Journal of Emergencies, Trauma and Shock, 2023
Hypogammaglobulinemia commonly presents with chronic diarrhea. Unfortunately, these patients require intravenous immunoglobulin (IVIG) transfusions of 400–800 mg/kg every 3–4 weeks as a standard treatment for hypogammaglobulinemia.
Pankaj Kumar, Thakur Prashant Singh, Amita Aggarwal, Praveer Rai, Amit Goel   +4 more
doaj   +1 more source

A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia

Annals of Thoracic Medicine, 2022
Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis.
Abeer N Alshukairi, Yasser A Aldabbagh, Najla M Sayes, Manal M Al Gethamy, Mohammed G Alghamdi, Zuhair A Rahbeeni, Ashraf Dada   +6 more
doaj   +1 more source

Humoral immune depression following autologous stem cell transplantation is a marker of prolonged response duration in patients with mantle cell lymphoma

Haematologica, 2022
Rituximab maintenance (RM) after autologous stem cell transplantation (ASCT) is standard-of-care for young patients with mantle cell lymphoma (MCL). RM may enhance post-transplantation immune depression and risk of infections.
Louise Bouard, Benoit Tessoulin, Catherine Thieblemont, Kamal Bouabdallah, Thomas Gastinne, Lucie Oberic, Sylvain Carras, Caroline Delette, Olivier Casasnovas, Caroline Dartigeas, Victoria Cacheux, Sibylle Masse, Olivier Hermine, Steven Le Gouill   +13 more
doaj   +1 more source

Hypogammaglobulinemia following COVID-19 infection in a patient on maintenance rituximab

SAGE Open Medical Case Reports, 2021
Hypogammaglobulinemia is a known side-effect of rituximab use. It is typically asymptomatic and transient, although certain factors, such as maintenance dosing and concomitant glucocorticoid use can lead to symptomatic or prolonged hypogammaglobulinemia.
Collin O’Bryan, Ronald Espinosa, Subramanyam Chittivelu   +2 more
doaj   +1 more source

Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study

Frontiers in Immunology, 2022
IKAROS and CTLA4 deficiencies are inborn errors of immunity and show similar clinical phenotypes, including hypogammaglobulinemia and autoimmune diseases (ADs).
Akihiro Hoshino, Akihiro Hoshino, Etsushi Toyofuku, Etsushi Toyofuku, Noriko Mitsuiki, Motoi Yamashita, Keisuke Okamoto, Michio Yamamoto, Kenji Kanda, Genki Yamato, Dai Keino, Yuri Yoshimoto-Suzuki, Junji Kamizono, Yasuhiro Onoe, Takuya Ichimura, Mika Nagao, Masaru Yoshimura, Koji Tsugawa, Toru Igarashi, Kanako Mitsui-Sekinaka, Yujin Sekinaka, Takehiko Doi, Takahiro Yasumi, Yozo Nakazawa, Masatoshi Takagi, Kohsuke Imai, Shigeaki Nonoyama, Tomohiro Morio, Sylvain Latour, Sylvain Latour, Hirokazu Kanegane   +30 more
doaj   +1 more source