Results 1 to 10 of about 19,833 (230)

Clinical and genetic features of UNC13D deficiency with hypogammaglobulinemia [PDF]

Frontiers in Immunology
BackgroundUNC13D deficiency is the most common form of familial hemophagocytic lymphohistiocytosis (FHL) in Asia. Hypogammaglobulinemia is a rare phenotype observed in both patients with FHL3 and sporadic hemophagocytic lymphohistiocytosis (HLH).
Linyan Xiong, Linyan Xiong, Linyan Xiong, Linyan Xiong, Qin Zhao, Qin Zhao, Qin Zhao, Qian Zhao, Qian Zhao, Qian Zhao, Zhiyong Zhang, Zhiyong Zhang, Zhiyong Zhang, Zhiyong Zhang, Yunfei An, Yunfei An, Yunfei An, Yunfei An, Xuemei Tang, Xuemei Tang, Xuemei Tang, Xuemei Tang, Hirokazu Kanegane, Xi Yang, Xi Yang, Xi Yang, Xi Yang, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao   +30 more
doaj   +2 more sources

Improving screening for antibody deficiency using calculated globulin and serum protein electrophoresis [PDF]

Frontiers in Immunology
PurposeAntibody deficiencies, particularly Common Variable Immunodeficiency (CVID), represent a major health concern due to comorbidities linked to delayed diagnosis.
Linda Mokrane, Azzeddine Tahiat, Sihem Taguemount, Hassen Messaoudi, Nadia Boukhenfouf, Abdelbassat Ketfi, Leila Smati, Rachida Boukari, Kamel Djenouhat   +8 more
doaj   +2 more sources

Prevalence of hypogammaglobulinemia after non-anti-CD20 therapies and impact of switching to rituximab/ocrelizumab in multiple sclerosis [PDF]

Neurotherapeutics
Some people with multiple sclerosis (PwMS) exhibit reduced serum immunoglobulin (Ig) levels, potentially due to disease-modifying therapies (DMTs), which raises concerns about initiating anti-CD20 therapies.
Marine Perriguey, Camille Rigollet, Sean A. Freeman, Lisa Graille-Avy, Jean-Christophe Lafontaine, Bruno Lemarchant, Tifanie Alberto, Sarah Demortière, Clémence Boutiere, Audrey Rico, Frédéric Hilézian, Pierre Durozard, Jean Pelletier, Adil Maarouf, Hélène Zéphir, Bertrand Audoin   +15 more
doaj   +2 more sources

CART CELL THERAPY BLACK SHADOW IN HEMATOLOGICAL DISORDERS : SYSTEMIC REVIEW WITH META-ANALYSIS

Hematology, Transfusion and Cell Therapy, 2022
Aim: To determine the effect of CART therapy on hypogammaglobulinemia and bone marrow aplasia, and to determine the probable medications in management of hypogammaglobulinemia with other associated risk factors and complications.
Ghada EL Gohary
doaj   +1 more source

Fresh-frozen plasma as a low-cost replacement of intravenous immunoglobulin for the treatment of symptomatic hypogammaglobulinemia

Journal of Emergencies, Trauma and Shock, 2023
Hypogammaglobulinemia commonly presents with chronic diarrhea. Unfortunately, these patients require intravenous immunoglobulin (IVIG) transfusions of 400–800 mg/kg every 3–4 weeks as a standard treatment for hypogammaglobulinemia.
Pankaj Kumar, Thakur Prashant Singh, Amita Aggarwal, Praveer Rai, Amit Goel   +4 more
doaj   +1 more source

Rituximab-Containing Treatment Regimens May Imply a Long-Term Risk for Difficult-To-Treat Chronic Hepatitis E [PDF]

, 2020
Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries which is usually characterized by a self-limited course. However, there is an increased risk of HEV persistence in immunocompromised risk populations, comprising ...
Biedermann, Paula, Bock, Claus-Thomas, Choi, Mira, Hanitsch, Leif Gunnar, Hofmann, Jörg, Mueller, Tobias, Schulz, Marten, Tacke, Frank   +7 more
core   +1 more source

A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia

Annals of Thoracic Medicine, 2022
Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis.
Abeer N Alshukairi, Yasser A Aldabbagh, Najla M Sayes, Manal M Al Gethamy, Mohammed G Alghamdi, Zuhair A Rahbeeni, Ashraf Dada   +6 more
doaj   +1 more source

Humoral immune depression following autologous stem cell transplantation is a marker of prolonged response duration in patients with mantle cell lymphoma

Haematologica, 2022
Rituximab maintenance (RM) after autologous stem cell transplantation (ASCT) is standard-of-care for young patients with mantle cell lymphoma (MCL). RM may enhance post-transplantation immune depression and risk of infections.
Louise Bouard, Benoit Tessoulin, Catherine Thieblemont, Kamal Bouabdallah, Thomas Gastinne, Lucie Oberic, Sylvain Carras, Caroline Delette, Olivier Casasnovas, Caroline Dartigeas, Victoria Cacheux, Sibylle Masse, Olivier Hermine, Steven Le Gouill   +13 more
doaj   +1 more source

Hypogammaglobulinemia following COVID-19 infection in a patient on maintenance rituximab

SAGE Open Medical Case Reports, 2021
Hypogammaglobulinemia is a known side-effect of rituximab use. It is typically asymptomatic and transient, although certain factors, such as maintenance dosing and concomitant glucocorticoid use can lead to symptomatic or prolonged hypogammaglobulinemia.
Collin O’Bryan, Ronald Espinosa, Subramanyam Chittivelu   +2 more
doaj   +1 more source

Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study

Frontiers in Immunology, 2022
IKAROS and CTLA4 deficiencies are inborn errors of immunity and show similar clinical phenotypes, including hypogammaglobulinemia and autoimmune diseases (ADs).
Akihiro Hoshino, Akihiro Hoshino, Etsushi Toyofuku, Etsushi Toyofuku, Noriko Mitsuiki, Motoi Yamashita, Keisuke Okamoto, Michio Yamamoto, Kenji Kanda, Genki Yamato, Dai Keino, Yuri Yoshimoto-Suzuki, Junji Kamizono, Yasuhiro Onoe, Takuya Ichimura, Mika Nagao, Masaru Yoshimura, Koji Tsugawa, Toru Igarashi, Kanako Mitsui-Sekinaka, Yujin Sekinaka, Takehiko Doi, Takahiro Yasumi, Yozo Nakazawa, Masatoshi Takagi, Kohsuke Imai, Shigeaki Nonoyama, Tomohiro Morio, Sylvain Latour, Sylvain Latour, Hirokazu Kanegane   +30 more
doaj   +1 more source