Results 21 to 30 of about 12,886 (187)
Mulibrey nanism and immunological complications: a comprehensive case report and literature review
Frontiers in Immunology, 2023 IntroductionMulibrey nanism (MUL) is a rare disorder caused by TRIM37 gene variants characterized by growth failure, dysmorphic features, congestive heart failure (CHF), and an increased risk of Wilms’ tumor.
Andrea Gazzin +15 more
doaj +1 more source
In-depth blood immune profiling of Good syndrome patients
Frontiers in Immunology, 2023 IntroductionGood syndrome (GS) is a rare adult-onset immunodeficiency first described in 1954. It is characterized by the coexistence of a thymoma and hypogammaglobulinemia, associated with an increased susceptibility to infections and autoimmunity.
Alba Torres-Valle +37 more
doaj +1 more source
Clinical Immunology CommunicationsHypogammaglobulinemia is a known side effect of rituximab (RTX) in adults, but its prevalence and persistence in children remain underexplored. This retrospective cohort study at a tertiary care center examines the prevalence and clinical outcomes of ...
Susanna P.C. Höppener +9 more
doaj +1 more source
Resistant Widespread Facial Impetigo in a Healthy Infant with Atopic Dermatitis [PDF]
Journal of Clinical and Diagnostic Research, 2018 Atopic Dermatitis (AD) or eczema is a chronic and relapsing, itchy skin inflammatory condition in infancy and childhood. The diagnosis is based on pruritus and an eczematous dermatitis with typical presentation.
Seyed Hesamedin Nabavizadeh +4 more
doaj +1 more source
Is Rituximab-Associated Hypogammaglobulinemia Always Linked to B-Cell Depletion?
Children, 2022 We describe a case of a 3-year-old male toddler with a history of severe and refractory warm antibody autoimmune hemolytic anemia (w-AIHA) since early infancy and hypogammaglobulinemia persisting 20 months after rituximab administration (second-line ...
Anthie Damianaki +6 more
doaj +1 more source
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
Frontiers in Medicine, 2021 Lupus nephritis in the context of Systemic Lupus Erythematosus (SLE) is characterized by an unpredicted course with remissions and flare-ups. Among others, it remains a significant cause of end-stage kidney disease (ESKD) in relatively young patients ...
Paraskevi Pavlakou +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Monoclonal gammopathy in WHIM syndrome can mask hypogammaglobulinemia
Journal of Allergy and Clinical Immunology: GlobalMonoclonal gammopathy can be seen at an early age in patients with warts-hypogammaglobulinemia, infections, and myelokathexis syndrome and can mask the presence of hypogammaglobulinemia.
Julia Lew, MD, Adil Adatia, MD
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source