Results 41 to 50 of about 12,886 (187)

Challenges in the Role of Gammaglobulin Replacement Therapy and Vaccination Strategies For Haematological Malignancy.

Frontiers in Immunology, 2016
Patients with chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are prone to present with antibody production deficits associated with recurrent or severe bacterial infections that might benefit from human immunoglobulin (Ig) (IVIg/SCIg ...
Silvia Sánchez-Ramón, Fatima Dhalla, Helen Chapel, Helen Chapel   +3 more
doaj   +1 more source

Rituximab Associated Hypogammaglobulinemia in Autoimmune Disease

Frontiers in Immunology, 2021
ObjectiveTo evaluate the characteristics of patients with autoimmune disease with hypogammaglobulinemia following rituximab (RTX) and describe their long-term outcomes, including those who commenced immunoglobulin replacement therapy.MethodsPatients ...
Joanna Tieu, Joanna Tieu, Joanna Tieu, Rona M. Smith, Rona M. Smith, Seerapani Gopaluni, Seerapani Gopaluni, Dinakantha S. Kumararatne, Mark McClure, Mark McClure, Ania Manson, Sally Houghton, David R. W. Jayne, David R. W. Jayne   +13 more
doaj   +1 more source

Successfully performed video capsule endoscopy in an 8‐month‐old infant weighing 7.5 kg

JPGN Reports, EarlyView.
Abstract Video capsule endoscopy (VCE) is a well‐established diagnostic tool for examining the small bowel. Limited data exist on its use in infants. To our knowledge, we present the first detailed case of a successful PillCam®SB3‐VCE performed in an 8‐month‐old infant weighing 7.5 kg with suspected small bowel bleeding following allogeneic ...
Paul‐Christoph Zeisler, Robert Thimme, Ulrike Teufel‐Schaefer, Michael Schultheiß   +3 more
wiley   +1 more source

Anti CD20 induced hypogammaglobulinemia in multiple sclerosis and neuromyelitis optica spectrum disorder: a cross sectional study

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Multiple sclerosis (MS) and Neuromyelitis Optica Spectrum Disorder (NMOSD) are chronic neurological conditions that carry significant morbidity and mortality. Anti-CD20 agents are a class of monoclonal antibodies that are used in the treatment
Ibrahim ElGarhy, Ayman Mohamed Ahmed Nassef, Mohamed Mahmoud Fouad, Dalia Samaha, Mahmoud Saad Swelam   +4 more
doaj   +1 more source

Strongyloides Hyperinfection and Hypogammaglobulinemia [PDF]

Clinical and Vaccine Immunology, 2005
ABSTRACT We report strongyloides hyperinfection in two patients with generalized hypogammaglobulinemia from multiple myeloma and nephrotic syndrome, despite a significant strongyloides-specific immunoglobulin G (IgG) response. In contrast to reports on animals, where human IgG was shown to be a protective antibody, our observation suggests ...
Seet, R.C.S., Lau, L.G., Tambyah, P.A.
openaire   +2 more sources

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

JEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz, Lars Matthies, Andrea Vanegas Ramirez   +2 more
wiley   +1 more source

Antibiotic Allergies in Pediatric Patients Diagnosed with Hypogammaglobulinemia

Journal of Human Immunity
RationaleHypogammaglobulinemia increases the risk of life-threatening bacterial infections that require antibiotic treatment in pediatric patients.
Aden Goolsbee, Aisha Ahmed, Elizabeth Lippner   +2 more
doaj   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

Rheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Clinical and genetic features of UNC13D deficiency with hypogammaglobulinemia

Frontiers in Immunology
BackgroundUNC13D deficiency is the most common form of familial hemophagocytic lymphohistiocytosis (FHL) in Asia. Hypogammaglobulinemia is a rare phenotype observed in both patients with FHL3 and sporadic hemophagocytic lymphohistiocytosis (HLH).
Linyan Xiong, Linyan Xiong, Linyan Xiong, Linyan Xiong, Qin Zhao, Qin Zhao, Qin Zhao, Qian Zhao, Qian Zhao, Qian Zhao, Zhiyong Zhang, Zhiyong Zhang, Zhiyong Zhang, Zhiyong Zhang, Yunfei An, Yunfei An, Yunfei An, Yunfei An, Xuemei Tang, Xuemei Tang, Xuemei Tang, Xuemei Tang, Hirokazu Kanegane, Xi Yang, Xi Yang, Xi Yang, Xi Yang, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao   +30 more
doaj   +1 more source