Results 61 to 70 of about 1,062,874 (251)

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer

Science Progress
Objective The purpose of this study is to further investigate the diagnostic value and precise localization of 68 Gallium prostate-specific membrane antigen positron emission tomography/computed tomography ( 68 Ga-PSMA PET/CT) for preoperative pelvic ...
Zhiqiang Qin, Gaojian Pan, Wen Huang, Luwei Xu, Ruipeng Jia   +4 more
doaj   +1 more source

The need for ‘Good Clinical Practice’ in health care research

South African Family Practice, 2009
Randomised controlled trials form the foundation for ‘evidence-based-medicine’, but the results of such research can be relied upon only if it was conducted according to principles and standards collectively referred to as ‘Good Clinical Practice’ (GCP).
M.H.R. NoorZurani, NorAzah Aziz, Aznida F. Abdul Aziz, Mohd Z. Abd Hamid, Mohazmi Mohamed, Sajaratulnisah Othman, N. Hussein   +6 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Safety Profile of Intravenous Ferulic Acid Nanoparticles: Acute Toxicity and Neurological Effects in Sprague-Dawley Rats

Nanotechnology, Science and Applications
Hao Huang,1,2,* Yan Xuan,3,* Zeng-Chun Ma4 1GCP Institutional Office, The First People’s Hospital of Neijiang, Neijiang, Sichuan, 641000, People’s Republic of China; 2Department of Clinical Pharmacy, Chengdu Qingbaijiang District People’s
Huang H, Xuan Y, Ma ZC
doaj  

EUPATI and Patients in Medicines Research and Development: Guidance for Patient Involvement in Regulatory Processes

Frontiers in Medicine, 2018
The importance and merits of greater patient involvement in medicines research and development (R&D) are commonly acknowledged and is thought to offer benefits for all involved parties.
David Haerry, Cordula Landgraf, Kay Warner, Amy Hunter, Ingrid Klingmann, Matthew May, Wolf See   +6 more
doaj   +1 more source

Good clinical practice in clinical interventional studies

European Clinical Respiratory Journal, 2014
Good clinical practice (GCP) guidelines should always be implemented and obeyed in clinical interventional studies. In this mini-review, we will address several burning questions relating to GCP in a concise 'frequently asked questions' format. While compliance to current rules and regulations is our mission, we also wish to play devil's advocate ...
Pieterse, Herman, Diamant, Zuzana
openaire   +3 more sources

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Clinical trials with Good Clinical Practice

Acta Médica del Centro, 2014
A standard for the conduct of clinical trials and to ensure quality constitute Good Clinical Practice, which are aimed at ensuring publicly protection of subjects participating in the trials and ensure the credibility of the data obtained and based on ...
Nerelys Díaz Lima, Aimeé Hurtado Pérez, María Margarita Ríos Cabrera   +2 more
doaj