Results 81 to 90 of about 1,091,889 (296)

Impact of educational intervention on knowledge, attitude and awareness of good clinical practice among health care providers

Perspectives in Clinical Research, 2017
Background: Clinical trials play an important role in the generation of evidence-based data in health care practices. To ensure the credibility of data and the safety and well-being of the patients Good clinical practice (GCP) guidelines play an ...
Divya Goel, Rani Walia, Poonam Sharma, Harmanjeet Kaur, Pallak Agnihotri   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Attracting psychologists to learning disability services: starting with assistants

, 2005
Assistants employed in a split support worker/psychology assistant post rated the experience of working with people with a learning disability positively and as an opportunity to increase knowledge of clinical psychology theory and its direct application
MacDonald, Kirsty, McKenzie, Karen, Wilson, Suzanne   +2 more
core  

Prevention of falls network Europe: A thematic network aimed at introducing good practice in effective falls prevention across Europe

, 2004
The Prevention of Falls Network Europe (ProFaNE) aims to improve quality of life of the ageing population by focussing on a major cause of disability and distress: falls.
Yardley, L., C. J. Todd, Skelton, D.A., Becker, C., C. Becker, S. E. Lamb, Todd, C., L. Yardley, W. Zijlstra, D. A. Skelton, Close, J.C.T., Zijlstra, W., J. C. T. Close, Lamb, S.E.   +13 more
core   +1 more source

The landscape of recurrent spontaneous abortion registered on clinical trials.gov

Frontiers in Endocrinology
ObjectiveRecurrent spontaneous abortion (RSA) presents a significant challenge in the field of reproductive medicine, as effective treatments remain limited despite extensive research efforts.
Xiaoling Zhou, Fan Lai, Wei Chen, Congrong Zhou, Yi Deng, Tao Wang, Shasha Xing, Haoyang Diao, Mi Tang, Wenmei Guo, Erdan Luo   +10 more
doaj   +1 more source

A multicenter, longitudinal, interventional, double blind randomized clinical trial in hematopoietic cell transplant recipients residing in remote areas: Lessons learned from the late cytomegalovirus prevention trial

Contemporary Clinical Trials Communications, 2016
Purpose: The logistics of conducting double-blinded phase III clinical trials with participants residing in remote locations are complex. Here we describe the implementation of an interventional trial for the prevention of late cytomegalovirus (CMV ...
Louise E. Kimball, Terry Stevens-Ayers, Margaret L. Green, Hu Xie, Mary E.D. Flowers, Keith R. Jerome, Renee LeBlanc, Christi Dahlgren, W. Garrett Nichols, Roy F. Chemaly, G. Papanicolaou, Michael Boeckh   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Satisfactory, good and outstanding nurses: perceptions of nurses, their colleagues and patients

, 2012
All nurses must accept responsibility for their own professional competence and performance but it is often the case that there is a large disparity between those nurses who perform very well and those who perform less well.
Medigovich, Kristina
core  

Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer

Science Progress
Objective The purpose of this study is to further investigate the diagnostic value and precise localization of 68 Gallium prostate-specific membrane antigen positron emission tomography/computed tomography ( 68 Ga-PSMA PET/CT) for preoperative pelvic ...
Zhiqiang Qin, Gaojian Pan, Wen Huang, Luwei Xu, Ruipeng Jia   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source