Results 101 to 110 of about 14,696,344 (291)
Guide to REgional Good Practice eHealth
, 2007 This report shows the result of the work of IANIS+ eHealth work group (WG). The WG has collected regional eHealth experiences from around Europe through a number of activities: • Regional eHealth case studies of which 17 (from 15 regions) are shown in ...
Bai, Guohua, Malmqvist, Gustav
core +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Analysis Document on Cooperation and Good Practice
: This document is prepared to analyse the cooperation and good practice in Grid projects and describes BalticGrid project experience in cooperation and implementation of good ...
Slaidiņš, Ilmārs, Belmanis, Oļģerts
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
National Journal of Physiology, Pharmacy and PharmacologyBackground: Clinical trials aim to improve health care by reducing treatment costs, enhancing quality, and advancing the discovery of safe treatments. Notably, limited knowledge among resident doctors may impact research quality.
Firoz M Tadavi +5 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Satisfactory, good and outstanding nurses: perceptions of nurses, their colleagues and patients [PDF]
, 2012 All nurses must accept responsibility for their own professional competence and performance but it is often the case that there is a large disparity between those nurses who perform very well and those who perform less well.
Medigovich, Kristina
core
Diagnosis and management of gonorrhoea and syphilis : Short report
, 2019 45 p.ill.,1 INTRODUCTION 7 -- BACKGROUND 7 -- REMIT OF THE GUIDELINE 9 -- 1.2.1 Objectives of the guideline 9 -- 1.2.2 Patient-centered care 9 -- 2 METHODOLOGY 10 -- THE GUIDELINE DEVELOPMENT GROUP 10 -- CLINICAL RESEARCH QUESTIONS 10 -- GENERAL APPROACH
Jespers, Vicky
core +1 more source