Results 121 to 130 of about 1,062,874 (251)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Concordance between European medicine agency good clinical practice inspections and medical literature: a meta-research survey. [PDF]

BMC Med
Terré A, Becker O, Ioannidis JPA, Naudet F.   +3 more
europepmc   +1 more source

"How do I keep this live in my mind?" Allied Health Professionals' perspectives of barriers and enablers to implementing good clinical practice principles in research: a qualitative exploration. [PDF]

BMC Health Serv Res, 2023
Wenke R, Roberts S, Angus R, Owusu MA, Weir K.   +4 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Evolving Standards: Good Clinical Practice Insights from US FDA, MHRA UK, and Health Canada. [PDF]

Clin Pharmacol Ther
Grandinetti C, Budwal-Jagait M, Abid H, Gebbia E, Boley E, Williams L, Fisher A, Marcus L, Muldowney L, Sellers J, Wakelin-Smith J, Ayalew K.   +11 more
europepmc   +1 more source

Correction to: Descriptive Analysis of Good Clinical Practice Inspection Findings from U.S. Food and Drug Administration and European Medicines Agency. [PDF]

Ther Innov Regul Sci, 2022
Sellers JW, Mihaescu CM, Ayalew K, Kronstein PD, Yu B, Ning YM, Rodriguez M, Williams L, Khin NA.   +8 more
europepmc   +1 more source

Good Clinical Practice and Good Laboratory Practice

, 2009
Nathalie K. Zgheib, Stephanie L. Tomasic, Robert A. Branch   +2 more
openaire   +1 more source

Good Clinical Practice [PDF]

Journal of pharmacology & clinical research, 2019
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Descriptive Analysis of Good Clinical Practice Inspection Findings from U.S. Food and Drug Administration and European Medicines Agency. [PDF]

Ther Innov Regul Sci, 2022
Sellers JW, Mihaescu CM, Ayalew K, Kronstein PD, Yu B, Ning YM, Rodriguez M, Williams L, Khin NA.   +8 more
europepmc   +1 more source