Results 91 to 100 of about 2,175,426 (304)

Aristotle’s Principles for Modern Economic Science

open access: yesStudia Gilsoniana, 2019
This paper is an attempt to illuminate today’s economic science with the light of Aristotle’s philosophy of economics. The author first describes Aristotle’s thoughts about the economy. Then, he distinguishes and discusses three Aristotelian principles: (
Ricardo F. Crespo
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Sustainable enterprise theory : a good life for all

open access: yes, 2017
This chapter develops a theory of sustainable enterprises, sustainable enterprise theory (SET), which can only be a valid theory if knowledge about life and nature is complete.
Cunningham, Gary, Fagerström, Arne
core  

Global to Village| A Dreamland or the Land of Broken Dreams: Juxtaposed Conceptions of the Good Life in Heyang

open access: yesInternational Journal of Communication, 2017
China’s rural villages, many of which are undergoing a great transformation from their communitarian past toward their fractured present, are significant sites of heightened inequalities unleashed during the reform era.
Xiaoxing Zhang
doaj  

The appeal of the good life: strategies for communicating sufficiency practices and policies

open access: yesSustainability: Science, Practice, & Policy
This article examines how sufficiency, an approach to sustainability focused on reducing resource consumption, can be communicated as a pathway to a good life rather than a call to sacrifice. Based on a representative survey in Germany, the findings show
Andrea Amri-Henkel   +7 more
doaj   +1 more source

‘He Is, After All, a Young Man’: Claiming Ordinary Lives for Young Adults with Profound Intellectual Disabilities

open access: yesScandinavian Journal of Disability Research, 2019
This paper discusses youth and the significance of age in the lives of persons with profound intellectual and multiple disabilities. The analysis is based on an ethnographic research project that explores what makes a good life for this group of people ...
Reetta Mietola, Simo Vehmas
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Quality of life among older people with poor functioning. The influence of perceived control over life

open access: yes, 2007
Objective: to investigate the apparently incongruous coupling of poor physical functioning with high QoL.Study design and setting: face-to-face interview survey of random sample of 999 people aged 65+ across Britain.Results: twenty-one per cent of ...
Morris, R   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy