Results 111 to 120 of about 2,175,426 (304)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The good life through good works

open access: yes, 2002
review of Good Work: When Excellence and Ethics Meet, by H. Gardner, M.
Borgmann, Albert
core  

How Government Stereotypes Affect Life Satisfaction: a Good Government Matters More Than a Government That Does Good

open access: yes
Many studies have noted the close relationship between the government and people's life satisfaction. However, little literature has paid attention to the role of government stereotypes. This research fills this gap using two large samples of Chinese
Zhou, Jie   +3 more
core   +1 more source

Examining the claim that 80-90% of suicide cases had depression

open access: yesFrontiers in Public Health, 2013
Said eShahtahmasebi   +2 more
doaj   +1 more source

Wisdom in the Old Testament

open access: yesSt Andrews Encyclopaedia of Theology
This article takes a thematic approach to commonalities between the three main wisdom books in the Old Testament/Hebrew Bible (OT/HB; sections 1–3), and then looks briefly at apocryphal and New Testament (NT) developments (section 4).
Katharine Dell
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Dying of cancer : is it the process or the place that contributes to a good death?

open access: yes, 2012
Includes abstract.Includes bibliographical references.This Quantitative Study undertook to investigate what family members or caregivers of deceased patients from a private oncology unit in Cape Town experienced during the last week of that patient’s ...
Manicom, Clare Louise
core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Oral History Interview with Donald Good, November 10, 2005

open access: yes, 2005
The National Museum of the Pacific War presents an interview with Donald Good. Mrs. Good assists with the interview. Good went into the Army in October 1941. He landed at Normandy with the 178th Signal Repair Company. He relates a few anecdotes about his
Good, Donald
core  

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