Results 131 to 140 of about 1,908,922 (262)

Does the good life feel good? The role of positive emotion in competing conceptions of the good life. [PDF]

Front Psychol
Novak L, Kiknadze N.
europepmc   +1 more source

Dogs and the Good Life: A Cross-Sectional Study of the Association Between the Dog-Owner Relationship and Owner Mental Wellbeing. [PDF]

Front Psychol, 2022
Merkouri A, Graham TM, O'Haire ME, Purewal R, Westgarth C.   +4 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Death attitudes and good life experience: the mediation and suppression effects of intrinsic and extrinsic goals. [PDF]

Front Psychiatry
Wang Y, Pei F, Yang Y, Wang J.
europepmc   +1 more source

A "Good Life" for Dairy Cattle: Developing and Piloting a Framework for Assessing Positive Welfare Opportunities Based on Scientific Evidence and Farmer Expertise. [PDF]

Animals (Basel), 2022
Stokes JE, Rowe E, Mullan S, Pritchard JC, Horler R, Haskell MJ, Dwyer CM, Main DCJ.   +7 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ecological limits: Science, justice, policy, and the good life. [PDF]

Philos Compass, 2021
Green F.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Challenging the Good Life: An Institutional Theoretic Investigation of Consumers' Transformational Process Toward Sustainable Living. [PDF]

J Bus Ethics, 2023
Ezell D, Bush V, Shaner MB, Vitell S, Huang J.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source