Results 151 to 160 of about 2,175,426 (304)

Struggling to Keep Up and Have a Good Life: A Qualitative Study of Living With Impaired Balance Control Due to Multiple Sclerosis. [PDF]

Phys Ther, 2023
Wallin A, Franzén E, Ekman U, Johansson S.   +3 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Retracted: Research on a Good Life and Coordinated Development Based on Intelligent Communication and k-Means Algorithm. [PDF]

J Healthc Eng, 2022
Engineering JOH.
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Supporting a 'good life' for autistic children: Autistic adults' and parents' perspectives. [PDF]

Autism
Simpson K, Allen C, Wheeley E, Pellicano E, Heyworth M, den Houting J, Bowen R, Adams D.   +7 more
europepmc   +1 more source

From the Good Life to Good Living: A Longitudinal Study Investigating the Relationship Between Good-Life Coherence and Motivation, Goal Progress and Subjective Well-Being. [PDF]

J Happiness Stud, 2022
Thomas B, Clegg KA, Holding AC, Koestner R.   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Good for Living? On the Relation between Globalization and Life Expectancy [PDF]

This paper analyzes the relation between three dimensions of globalization (economic, social and political) and life expectancy using a panel of 92 countries over the period 1970-2005.
Nilsson, Therese, Bergh, Andreas
core  

The Good Life with Dementia approach: A realist-informed qualitative study of a peer-tutored course, co-produced with and for people living with dementia. [PDF]

PLoS One
Gridley K, Wilberforce M, Mann R, Tucker L, Casey B, Clarke C, Creavin S, Donaldson I, Gordon H, Murphy D, Pearson M, Rauf MA, Birks Y.   +12 more
europepmc   +1 more source

What is a "Good Life": Protocol for a qualitative study to explore the viewpoint of older persons. [PDF]

PLoS One, 2021
Michel H, Prévôt-Huille H, Koster R, Ecarnot F, Grange Z, Sanchez S.   +5 more
europepmc   +1 more source