Results 171 to 180 of about 858,465 (296)

Patient and physician preferences for treatment of hepatitis C virus infection in Japan: a discrete choice experiment: plain language summary of publication. [PDF]

Ther Adv Gastroenterol
Nakamoto D, Piao Y, Yoshida M, LoPresti M, Makhija D, Kwon KM, Zagorski J, Jinushi M, Eguchi Y.   +8 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Care Deliberations of Family Carers of People Living With Dementia-Applying an Affective-Discursive Practices Approach. [PDF]

Sociol Health Illn
Lönnroth M, Halonen U, Leinonen E, Aerschot LV.   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Perceptions, beliefs, and experiences of living with osteoporosis among UK South Asian older women. [PDF]

Arch Osteoporos
Shafiq S, Kime N, Johansson JF, Teale E, Connor J, Sharp C, Heaven A.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Good living tourism : lifestyle aspects of food and wine tourism

, 2005
Davies, Jenny, Sparks, Beverley, Brown, Lorraine, Roberts, Linda Margaret, Deery, Margaret   +4 more
core  

Quality of life and associated factors among people living with hypertension in a tertiary hospital of Kathmandu District, Nepal. [PDF]

BMC Cardiovasc Disord
Ghimire D, Poudel S, Parajuli A, Parajuli AR, Karki S, Bhandari GP.   +5 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Urban-rural disparities in living arrangement and older adults care service supply in China: a cross-sectional study. [PDF]

Front Public Health
Xiao P, Wang X, Xu D, Gao Y.
europepmc   +1 more source