Results 181 to 190 of about 780,888 (250)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Health status of living kidney donors and attitude toward donation-Results from the German Living Donor Registry (SOLKID-GNR). [PDF]

Front Med (Lausanne)
Suwelack B, Kröncke S, Wegner J, Bormann E, Gerß J, Riepenhausen S, Neuhaus P, Storck M, Koch M, Sommerer C.   +9 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Development of a Japanese version of the Family Stigma Instrument for dementia. [PDF]

Alzheimers Dement (Amst)
Noguchi T, Bhatt J, Komatsu A, Watanabe R.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Young Adults' Views on Priority Health Issues and Their Involvement in Shaping Responses: A Qualitative Exploration in South Australia. [PDF]

Health Promot J Austr
Castleton P, Padhani ZA, Kurji J, Vass S, Ataie S, Meherali S, Lassi ZS.   +6 more
europepmc   +1 more source

Physical activity and diabetes in german primary care: a qualitative interview study with individuals living with diabetes. [PDF]

BMC Prim Care
Lindner N, Friedrich L, Kornder N, Becker A, van der Wardt V.   +4 more
europepmc   +1 more source

Development of Data-Driven Models for Just-in-Time Digital Self-Management Advice to Improve Physical Functioning in Hip and Knee Osteoarthritis: Protocol for the e-cOAch Cross-Over Study. [PDF]

JMIR Res Protoc
Groen F, de Rooij M, Kloek CJJ, Veenhof C, Klein MCA, Al-Janabi A, van Haeringen ES, Ronteltap A, Paans-Cijs B, van Dongen B, Ginsel DE, Barten DA, Hoogeboom TJ, Pisters MF.   +13 more
europepmc   +1 more source

Machine Learning in HIV Care and Antiretroviral Therapy: Systematic Review. [PDF]

J Med Internet Res
Boudra T, Idrissou A, Barakat O, Davani S, Valnet Rabier MB, Lagoutte-Renosi J.   +5 more
europepmc   +1 more source