Results 41 to 50 of about 575,729 (287)
Jurnal Pendidikan Ekonomi dan Bisnis (JPEB), 2017 The purpose of this research to create the boder region of investment development model, the maritime industry investment development model and Free Trade Zone development model effect on increase the welfare of coastal communities.The research location ...
Tumpal Manik +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Goodness of Fit Test and Test of Independence by Entropy
Journal of Mathematical Extension, 2009 To test whether a set of data has a specific distribution or not, we can use the goodness of fit test. This test can be done by one of Pearson X 2 -statistic or the likelihood ratio statistic G 2 , which are asymptotically equal, and also by using
M. Sharifdoost, N. Nematollahi, E. Pasha
doaj
Goodness-of-Fit Test of Shapiro-Wilk Type with Nuisance Regression and Scale
Austrian Journal of Statistics, 2016 Shapiro and Wilk (1965) proposed a highly intuitive goodness-of-fit test of normality with nuisance location and scale parameters. The test has received a considerable attention in the literature; its asymptotic null distribution is covered by the ...
Pranab Kumar Sen +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Informative Features for Model Comparison [PDF]
, 2018 Given two candidate models, and a set of target observations, we address the problem of measuring the relative goodness of fit of the two models. We propose two new statistical tests which are nonparametric, computationally efficient (runtime complexity ...
Gretton, Arthur +5 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Goodness-of-Fit Tests in Nonparametric Regression [PDF]
SSRN Electronic Journal, 2006 AMS classifications: 62G08, 62G10, 62G20, 62G30; 60F17.
Einmahl, J.H.J., Keilegom, I. van
openaire +8 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source