Results 51 to 60 of about 349,134 (285)

Evaluating the Three Methods of Goodness of Fit Test for Frequency Analysis [PDF]

open access: yesJournal of Risk Analysis and Crisis Response (JRACR), 2015
In hydrological statistics, the traditional assessment of goodness of fit test is interested in the testing precision to the sample generated from supposed PDF.
Xiankui Zeng, Dong Wang, Jichun Wu
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Goodness-of-fit Testing for Left-truncated Two-parameter Weibull Distributions with Known Truncation Point

open access: yesAustrian Journal of Statistics, 2016
The left-truncated Weibull distribution is used in life-time analysis, it has many applications ranging from financial market analysis and insurance claims to the earthquake inter-arrival times.
Ayse KIZILERSU   +2 more
doaj   +1 more source

Investigating the Factors Affecting Depression By Using Structural Equation Modeling

open access: yesGalician Medical Journal, 2021
The objective of the research was to study the factors affecting depression in general population. Materials and Methods. A total of 1,291 individuals at the age of 15-68 years participated in this cross-sectional study.
Meryem Firat   +4 more
doaj   +1 more source

Estimation of integrated volatility of volatility with applications to goodness-of-fit testing

open access: yes, 2015
In this paper, we are concerned with nonparametric inference on the volatility of volatility process in stochastic volatility models. We construct several estimators for its integrated version in a high-frequency setting, all based on increments of spot ...
Vetter, Mathias
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Construction of a geographically weighted nonparametric regression model fit test

open access: yesMethodsX
One of the approach of Geographically Weighted Regression (GWR) models is the Geographically Weighted Nonparametric Regression (GWNR) has more parameters than the GWR model.
Lilis Laome   +2 more
doaj   +1 more source

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