Results 41 to 50 of about 814 (166)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Goodness-of-fit Testing for Left-truncated Two-parameter Weibull Distributions with Known Truncation Point

Austrian Journal of Statistics, 2016
The left-truncated Weibull distribution is used in life-time analysis, it has many applications ranging from financial market analysis and insurance claims to the earthquake inter-arrival times.
Ayse KIZILERSU, Markus Kreer, Anthony W. Thomas   +2 more
doaj   +1 more source

A Correlation Type Goodness of Fit Test for the Burr Distribution [PDF]

The Egyptian Statistical Journal, 1996
The Burr family of distributions is widely used in life testing studies. The two common survival or failure-time distributions, the Weibull and the Exponential, are both special cases or limiting cases of the Burr type XII (see Lewis (1981), denoted by ...
Abd-Allah Abd-Elfattah
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Construction of a geographically weighted nonparametric regression model fit test

MethodsX
One of the approach of Geographically Weighted Regression (GWR) models is the Geographically Weighted Nonparametric Regression (GWNR) has more parameters than the GWR model.
Lilis Laome, I Nyoman Budiantara, Vita Ratnasari   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Robustness of the Trinormal ROC Surface Model: Formal Assessment via Goodness-of-Fit Testing

Stats
Receiver operating characteristic (ROC) surfaces provide a natural extension of ROC curves to three-class diagnostic problems. A key summary index is the volume under the surface (VUS), representing the probability that a randomly chosen observation from
Christos Nakas
doaj   +1 more source

Evaluating the Three Methods of Goodness of Fit Test for Frequency Analysis [PDF]

Journal of Risk Analysis and Crisis Response (JRACR), 2015
In hydrological statistics, the traditional assessment of goodness of fit test is interested in the testing precision to the sample generated from supposed PDF.
Xiankui Zeng, Dong Wang, Jichun Wu
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A Simple Method for Testing Independence of High-Dimensional Random Vectors

Austrian Journal of Statistics, 2016
A simple, data-driven and computationally efficient procedure for testing independence of high-dimensional random vectors is proposed. The procedure is based on interpretation of testing goodness-of-fit as the classification problem, a special sequential
Gintautas Jakimauskas, Marijus Radavičius, Jurgis Sušinskas   +2 more
doaj   +1 more source