Results 91 to 100 of about 166,159,676 (294)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Goodness of fit tests for random multigraph models. [PDF]

J Appl Stat, 2023
Shafie T.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Goodness and Lack of Fit Tests to Pretest Normality when Comparing Means [PDF]

Operations Research and Decisions
Previous studies show that processes related to traditional pretests to prove the perfect fulfillment of assumptions in comparison means tests lead to severe alterations in the overall Type I error probability and power.
Pablo Flores, María de Lourdes Palacios
doaj  

Goodness-of-fit tests in proportional hazards models with random effects. [PDF]

Biom J, 2023
González-Manteiga W, Martínez-Miranda MD, Van Keilegom I.   +2 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Goodness of fit in models for mortality data [PDF]

, 2008
Mortality data on an aggregate level are characterized by very large sample sizes. For this reason, uninformative outcomes are evident in common Goodness-of-Fit measures.
Camarda, Carlo Giovanni, Durbán Reguera, María Luz   +1 more
core   +1 more source

Pearson's goodness-of-fit tests for sparse distributions. [PDF]

J Appl Stat, 2023
Chang S, Li D, Qi Y.
europepmc   +1 more source

Goodness-of-fit-indices of structural invariance between genders.

, 2019
Goodness-of-fit-indices of structural invariance between genders.
Pedro Duarte-Mendes (6729731), Carla Borrego (6691685), Diogo S. Teixeira (5082977), João M. Moutão (6729734), Diogo Monteiro (4893859), Ana Pires (4260214), Luis Cid (6729728)   +6 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source