Results 111 to 120 of about 102,684 (297)
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
A note on goodness of fit test using moments
The purpose of this article is to introduce a general moment-based approach to derive formal goodness of fit tests of a parametric family. We show that, in general, an approximate normal test or a chi-squared test can be derived by exploring the moment ...
Alex Papadopoulos, Gang Li
doaj +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Effect of estimation in goodness-of-fit tests
In statistical analysis, distributional assumptions are needed to apply parametric procedures. Assumptions about underlying distribution should be true for accurate statistical inferences.
EMRAH EREN
core
On goodness-of-fit tests for arbitrary multivariate models
Goodness-of-fit tests are often used in data analysis to test the agreement of a distribution to a set of data. These tests can be used to detect an unknown signal against a known background or to set limits on a proposed signal distribution in ...
Caldwell, Allen, Shtembari, Lolian
core +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Bootstrap methods for goodness-of-fit tests
Darba tēma ir butstrapa metode sadalījuma pārbaudes testiem. Tiek apskatīta šīs metodes ideja un pierādījumi. Ar piemēru palīdzību gan neparametriskā, gan parametriskā butstrapa metode pielietota statistikas sadalījumu meklēšanai.
Trautmane, Anna
core
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
A Chi-Square Statistic for Goodness-of-Fit Tests [PDF]
8 pages, 1 article*A Chi-Square Statistic for Goodness-of-Fit Tests* (Rao, K. C.; Robson, D.
Robson, D. S. +4 more
core

