Results 81 to 90 of about 316,861 (309)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Goodness-of-fit test for BTC/JPY.
, 2019 Goodness-of-fit test for BTC/JPY.
Mario I. Contreras-Valdez (6499304) +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A Comparative Study of Beauty and its Relation to Pleasure and Goodness in the Philosophy of Plotinus and Avicenna [PDF]
آموزههای فلسفه اسلاميThe truth and nature of beauty, as a secondary intelligible (Arabic: مَعْقولُ الْثَّانی, romanized: maʿqūl al-thānī), have become a topic of discussion among philosophers.
Muḥammūd Ṣeydiī +1 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Karhunen-loève basis in goodness-of-fit tests decomposition: an evaluation [PDF]
, 2006 In a previous paper (Grané and Fortiana 2006) we studied a flexible class of goodness-of-fit tests associated with an orthogonal sequence, the Karhunen-Loève decomposition of a stochastic process derived from the null hypothesis.
Grané Chávez, Aurea, Fortiana, Josep
core +1 more source
Climate Change and Virtue: An Apologetic
Humanities, 2014 The prominent Australian earth scientist, Tim Flannery, closes his recent book Here on Earth: A New Beginning with the words “… if we do not strive to love one another, and to love our planet as much as we love ourselves, then no further progress is ...
Mike Hulme
doaj +1 more source
Asymptotic properties of a goodness-of-fit test based on maximum correlations [PDF]
We study the efficiency properties of the goodness-of-fit test based on the Qn statistic introduced in Fortiana and Grané (2003) using the concepts of Bahadur asymptotic relative efficiency and Bahadur asymptotic optimality.
Aurea Grane, Anna V. Tchirina
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Calling as a Motivating Factor of the Development of Education in Ukraine
Філософія освіти, 2017 The article raises importance of the topic of mission in contemporary philosophy and educational sciences. Mission is a basic idea for building up of civil society as a community of responsible and committed people. Mission has a special significance for
Yevhen Ivanovych Muliarchuk
doaj +1 more source