Results 81 to 90 of about 317,930 (307)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Climate Change and Virtue: An Apologetic
Humanities, 2014 The prominent Australian earth scientist, Tim Flannery, closes his recent book Here on Earth: A New Beginning with the words “… if we do not strive to love one another, and to love our planet as much as we love ourselves, then no further progress is ...
Mike Hulme
doaj +1 more source
Testing EBUmgf Class of Life Distributions based on Goodness of Fit approach
Journal of Statistical Theory and Applications (JSTA), 2016 Based on the goodness of fit approach, a new test is presented for testing exponentiality against “exponential Better than Used in moment generating function ordering class” (EBUmgf). The critical values and the powers of this test are calculated.
A. Gadallah
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Calling as a Motivating Factor of the Development of Education in Ukraine
Філософія освіти, 2017 The article raises importance of the topic of mission in contemporary philosophy and educational sciences. Mission is a basic idea for building up of civil society as a community of responsible and committed people. Mission has a special significance for
Yevhen Ivanovych Muliarchuk
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FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Reading The Silence In The Maternal Text Of Carol Shields’ Unless
Gender Studies, 2014 This article scrutinizes the representation of silence in Carol Shields’ novel Unless. It analyses the problematic behind the mother-daughter relationship between Reta Winters and her daughter Norah by applying the theories of Cixous, Kristeva, Chodorow ...
İNCEOĞLU ŞEYDA
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Explanation of Goodness Concept in Good Governance [PDF]
مدیریت دولتی, 2009 Good governance is a fresh subjects regarded by authors and world scientific and international societies during two recent decades. Researches describe and define good governance through various approaches (process, liberalism, and socialism), dimensions
Soroush Dabbagh, Neda Nafari
doaj