Results 71 to 80 of about 176,715 (305)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
On Entropy Test for Conditionally Heteroscedastic Location-Scale Time Series Models
Entropy, 2017 This study considers the goodness of fit test for a class of conditionally heteroscedastic location-scale time series models. For this task, we develop an entropy-type goodness of fit test based on residuals.
Sangyeol Lee, Minjo Kim
doaj +1 more source
Bootstrap goodness-of-fit tests for farima models [PDF]
, 1999 This paper proposes goodness-of-fit tests for the class of covariance stationary FARIMA processes. They are based on functionals of weighted empirical processes, say Sn C.), where the weights are the relative error between the periodogram and the fitted ...
Delgado, Miguel A., Hidalgo, Javier
core
Goodness-of-fit test for BTC/JPY.
, 2019 Goodness-of-fit test for BTC/JPY.
Mario I. Contreras-Valdez (6499304) +2 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Goodness-of-fit test for BTC/BRL.
, 2019 Goodness-of-fit test for BTC/BRL.
Mario I. Contreras-Valdez (6499304) +2 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Frontiers in Psychology, 2018 The performance of the limited-information statistic M2 for diagnostic classification models (DCMs) is under-investigated in the current literature. Specifically, the investigations of M2 for specific DCMs rather than general modeling frameworks are ...
Fu Chen, Yanlou Liu, Tao Xin, Ying Cui
doaj +1 more source
Goodness-of-fit test for BTC/RMB.
, 2019 Goodness-of-fit test for BTC/RMB.
Mario I. Contreras-Valdez (6499304) +2 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source