Results 211 to 220 of about 14,116 (259)

Gossypol Clathrates. Structure of a Gossypol Complex with Isobutylacetate

Journal of Structural Chemistry, 2002
The natural compound gossypol forms stable clathrates with isobutylacetate. The clathrates were investigated by X-ray diffractometry. The crystallographic parameters of single crystals were determined and refined using 15 reflections on a Syntex P21 four-circle automatic diffractometer. The crystals are monoclinic, C30H30O8·0.5C6H12O2, a = 11.444(2), b
S. A. Talipov, B. T. Ibragimov
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Inhibition of Aldose Reductase by Gossypol and Gossypol-Related Compounds

1999
The aldo-keto reductases are a widely distributed family of oxidoreductases (Wirth and Wermuth, 1985; Wermuth, 1985; Grimshaw and Mathur, 1989). Aldose reductase (EC 1.1.1.21; ALR2; or AKR1B1 (Jez et al., 1997)), which has a role in the etiology of diabetic complications (Gabbay, 1973; Kador and Kinoshita, 1985), has received most attention as a ...
L M, Deck, B B, Chamblee, R E, Royer, L A, Hunsaker, D L, Vander Jagt   +4 more
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Reactions of proteins with gossypol

Archives of Biochemistry and Biophysics, 1959
Abstract Several methods for the preparation of protein-gossypol complexes are described. When gossypol combines with blood albumin or with cottonseed protein, the reaction is with the free e-amino groups of lysine. The ratio of moles of free lysine ϵ-amino groups which disappear to moles of gossypol combined with protein varies according to the ...
C M, LYMAN, B P, BALIGA, M W, SLAY
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Gossypol Detoxication by Fungi

Science, 1969
An unidentified Diplodia isolate representative of several fungi tested and grown for 13 days on gossypol-containing cottonseed reduced the amount of free gossypol by 90 percent and detoxified the cottonseed for weanling rats and chickens.
W L, Baugher, T C, Campbell
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Metabolism of gossypol in the chick

Journal of the American Oil Chemists' Society, 1969
Abstract14C labeled gossypol was administered to young chickens and the deposition of gossypol plus gossypol decomposition products in the various tissues was evaluated by determination of14C activity in a scintillation spectrometer. Most of the gossypol activity was recovered in the feces with relatively smaller amounts retained by the tissues.
C M, Lyman, J T, Cronin, M M, Trant, G V, Odell   +3 more
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Resolution of racemic gossypol

Journal of the Chemical Society, Chemical Communications, 1985
Racemic gossypol, a potential antifertility agent has been resolved through its derivatives with chiral 1-methylphen-ethylamine into (+)- and (–)-gossypol.
D K, Zheng, Y K, Si, J K, Meng, J, Zhou, L, Huang   +4 more
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Modified procedures for determination of gossypol pigments. II. Determination of free gossypol in low gossypol meals and of gossypol in oils

Journal of the American Oil Chemists' Society, 1968
AbstractMuch of the «free» gossypol in meals of low free gossypol content consists of «soluble‐bound» gossypol. Addition of dilute hydrochloric acid reduces the optical densities of gossypol blanks in free and total gossypol calibrations and assays. The reductions in these optical densities were lower than expected in free gossypol assays on meals of ...
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Resolution of racemic gossypol

Journal of Ethnopharmacology, 1987
Treating racemic gossypol with chiral amine (S)-1-methylphenethyl amine gave the expected pair of diastereomeric amino condensates in which the binaphthyl nuclei racemized during further treatment. Acetylation was applied to avoid the change. On acetylation, 7 products were separated.
L, Huang, D K, Zheng, Y K, Si
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Gossypol‐hypokalaemia interrelationships

International Journal of Andrology, 1985
Around 1% of 8806 volunteers taking gossypol as a male contraceptive had hypokalaemic paralysis and more had simple hypokalaemia, the direct cause being renal potassium loss. In gossypol takers not showing hypokalaemia, serum potassium levels were within the normal range but were significantly lower than levels in controls.
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Comparative spermicidal effects of (+)-gossypol, (+)-gossypol, (−)-gossypol and gossypolone

Contraception, 1984
I.C. Kim, D.P. Waller, G.B. Marcelle, G.A. Cordell, H.H.S. Fong, W.H. Pirkle, L. Pilla, S.A. Matlin   +7 more
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