Results 211 to 220 of about 14,284 (259)

Gossypol mediated DNA degradation

Biochemical and Biophysical Research Communications, 1987
Gossypol, a polyphenolic compound isolated from cotton plant was found to degrade pBR322 DNA in vitro in a reaction which required the presence of a metal ion, a reducing agent (2-mercaptoethanol) and oxygen as revealed after agarose gel electrophoresis.
Srivastava, AK, Padmanaban, G
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Gossypol Detoxication by Fungi

Science, 1969
An unidentified Diplodia isolate representative of several fungi tested and grown for 13 days on gossypol-containing cottonseed reduced the amount of free gossypol by 90 percent and detoxified the cottonseed for weanling rats and chickens.
W L, Baugher, T C, Campbell
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Resolution of racemic gossypol

Journal of the Chemical Society, Chemical Communications, 1985
Racemic gossypol, a potential antifertility agent has been resolved through its derivatives with chiral 1-methylphen-ethylamine into (+)- and (–)-gossypol.
D K, Zheng, Y K, Si, J K, Meng, J, Zhou, L, Huang   +4 more
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Resolution of racemic gossypol

Journal of Ethnopharmacology, 1987
Treating racemic gossypol with chiral amine (S)-1-methylphenethyl amine gave the expected pair of diastereomeric amino condensates in which the binaphthyl nuclei racemized during further treatment. Acetylation was applied to avoid the change. On acetylation, 7 products were separated.
L, Huang, D K, Zheng, Y K, Si
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Antifertility effect of polyvinylpyrrolidone-gossypol and gossypol in male rats

Contraception, 1985
Thirty-nine adult male Wistar rats were administered 20 mg/kg or 24.3 mg/kg polyvinylpyrrolidone-gossypol (PVP-G) and 20 mg/kg gossypol acetic acid (G-A) 6 times a week for 6 weeks. Mating test was taken to evaluate the antifertility effect. Caudal sperm count, body weight, sex and accessory sex organ weights were recorded.
Y, Wang, X Q, Shi, Y B, Sun
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Comparative in vitro spermicidal effects of (+/-)-gossypol, (+)-gossypol, (-)-gossypol and gossypolone.

Contraception, 1985
The comparative in vitro spermicidal effects of (+)-gossypol, (-)-gossypol and (+/-)-gossypol were evaluated on the spermatozoa of human, monkey, rabbit, mouse, rat and hamster. The spermicidal effects of gossypol isomers were also compared with those of gossypolone, which is a proposed major metabolite of gossypol.
I C, Kim, D P, Waller, G B, Marcelle, G A, Cordell, H H, Fong, W H, Pirkle, L, Pilla, S A, Matlin   +7 more
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Gossypol

2022
Idrees Ahmad Wani, Sadaf Nazir
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Comparative spermicidal effects of (+)-gossypol, (+)-gossypol, (−)-gossypol and gossypolone

Contraception, 1984
I.C. Kim, D.P. Waller, G.B. Marcelle, G.A. Cordell, H.H.S. Fong, W.H. Pirkle, L. Pilla, S.A. Matlin   +7 more
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Inhibition of Aldose Reductase by Gossypol and Gossypol-Related Compounds

1999
The aldo-keto reductases are a widely distributed family of oxidoreductases (Wirth and Wermuth, 1985; Wermuth, 1985; Grimshaw and Mathur, 1989). Aldose reductase (EC 1.1.1.21; ALR2; or AKR1B1 (Jez et al., 1997)), which has a role in the etiology of diabetic complications (Gabbay, 1973; Kador and Kinoshita, 1985), has received most attention as a ...
L M, Deck, B B, Chamblee, R E, Royer, L A, Hunsaker, D L, Vander Jagt   +4 more
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Highly Luminescent Lanthanide Metal‐Organic Frameworks with Tunable Color for Nanomolar Detection of Iron(III), Ofloxacin and Gossypol and Anti‐counterfeiting Applications

Angewandte Chemie - International Edition, 2023
Vladimir P Fedin
exaly