Results 51 to 60 of about 380,407 (196)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

The effect of coffee consumption on liver function in adult male rabbits

open access: yesKufa Journal for Veterinary Medical Sciences, 2011
This study was carried out on 10 adult male Rabbits to investigate  the effect of Coffee at a dose  ( 100 mg/ Kg B.W. / day) orally on the liver function by measuring the Liver enzymes such as [Glutamic Oxaloacetate transaminase (GOT) , Glutamic Pyruvic
Sabreen Majeed Mohammad Ali Mohammad Ali
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

A High-Fat Diet Induces Oxidative Stress in OPA1+/− Mouse Cortices: A Critical Double Challenge

open access: yesAntioxidants
A high-fat diet (HFD) has significant effects on health, leading to cardiovascular, metabolic, neurodegenerative, and psychiatric conditions and contributing to obesity and type 2 diabetes.
Camille Champigny   +7 more
doaj   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green   +6 more
wiley   +1 more source

Study of the Histological & Biochemical Effects of Hypothermia in Liver of Rats

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2004
Introduction: Hypothermia is used as an adjunct in surgery of different organs including heart, liver, brain and thyroid .It can be produced by different techniques such as superficial cooling ,cooling of blood and pharmacological cooling .
A Rahimipour   +2 more
doaj  

Disturbance of phosphatase and transaminase activities in grubs of the red palm weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae) by certain insecticidal compounds

open access: yesJournal of Basic and Applied Zoology, 2019
Background Serious damage of red palm weevil to date palm encourages its control by various measures. The present work was carried out to investigate the effects of some insecticides of different categories (Pyriproxyfen, Neemazal, and Spinetoram) on the
Khalid Sh. Hamadah
doaj   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein   +7 more
wiley   +1 more source

"Ain’t Got No Dream"

open access: yesArt/Research International
"Ain’t Got No Dream" is a 3-minute song that incorporates findings from the Transformative Compassion project as a means of knowledge mobilization.
Phillip Joy, Stephen Fewer
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

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