Results 251 to 260 of about 216,147 (379)

Feeling Lonely While Ageing in Place in the Netherlands: Questioning the Importance of Shopping Spaces for Older People

open access: yesTijdschrift voor Economische en Sociale Geografie, EarlyView.
Abstract More than half of the Dutch older population feels lonely, meaning their social relationships do not meet their needs. As people are predominantly ageing in place (AIP) instead of in care homes, their everyday experiences become more localised and neighbourhood spaces gain traction as important spaces of encounter.
Rianne van Melik, Daniëlle van der Lee
wiley   +1 more source

Risk of incident gout in rheumatoid arthritis from a nationwide cohort study in South Korea. [PDF]

open access: yesSci Rep
Kang S   +10 more
europepmc   +1 more source

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 20, Page 4876-4893, October 2025.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding   +5 more
wiley   +1 more source

Yawning as Therapy? The Potential of the Conditioned Yawn Reflex as a Novel Treatment for Insomnia Disorder

open access: yesJournal of Sleep Research, Volume 34, Issue 5, October 2025.
ABSTRACT In 1986, Provine, the pioneer of yawning research wrote that ‘Yawning may have the dubious distinction of being the least understood, common human behaviour’ (p. 120); and so yawning remains some 40 years later, as something of a biological and social curiosity.
Colin A. Espie
wiley   +1 more source

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