Results 71 to 80 of about 174,736 (301)

Masalah Utama Gout ( Asam Urat ) Khususnya pada Tn. S di Wilayah Kerja Puskesmas Gatak [PDF]

open access: yes, 2013
Latar Belakang : Banyak orang membicarakan penyakit gout (asam urat). Penyakit ini populer di kalangan masyarakat luas, sayang pemahaman paa penyakit ini sangat terbatas serta banyak orang salah memahami penyakit gout secara benar.
, H. M. Abi Muhlisin, SKM., M.Kep.   +1 more
core  

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Exploration of molecular biomarkers in ankylosing spondylitis transcriptomics

open access: yesFrontiers in Immunology
BackgroundInflammation of the spine and sacroiliac joints is a hallmark of the chronic, progressive inflammatory illness known as ankylosing spondylitis (AS). The insidious onset and non-specific early symptoms of AS often lead to delays in diagnosis and
Yuanpiao Ni   +13 more
doaj   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

open access: yesAdvanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang   +22 more
wiley   +1 more source

Management of Gout in the United States: A Claims‐based Analysis

open access: yesACR Open Rheumatology, 2020
Objective Gout is the most common inflammatory arthritis in the United States. Although numerous guidelines exist for the management of gout, they are not routinely implemented. This study evaluated the real‐world practice patterns in gout patients using
N. Lawrence Edwards   +4 more
doaj   +1 more source

Landau-Lifshitz hierarchy and infinite dimensional Grassmann variety

open access: yes, 2004
The Landau-Lifshitz equation is an example of soliton equations with a zero-curvature representation defined on an elliptic curve. This equation can be embedded into an integrable hierarchy of evolution equations called the Landau-Lifshitz hierarchy ...
Takasaki, Kanehisa
core   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

Approximate message passing for nonconvex sparse regularization with stability and asymptotic analysis

open access: yes, 2018
We analyse a linear regression problem with nonconvex regularization called smoothly clipped absolute deviation (SCAD) under an overcomplete Gaussian basis for Gaussian random data.
Sakata, Ayaka, Xu, Yingying
core   +1 more source

Onset of depression and anxiety among patients with gout after diagnosis: a population-based incident cohort study [PDF]

open access: gold, 2022
Alyssa Howren   +6 more
openalex   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

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