Results 91 to 100 of about 24,540 (201)

Association Between TyG‐WC and Gout in American Adults: A Cross‐Sectional Study of NHANES 2003–2018

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The triglyceride‐glucose (TyG) index is widely used as a surrogate marker of insulin resistance. Indices that combine TyG with anthropometric measures may better reflect metabolic dysfunction and central adiposity. However, evidence regarding the association between TyG‐waist circumference (TyG‐WC) and gout among U.S ...
Shenlong Yi, Keyu Tao, Menglin Fan, Zicong Ren, Wei Wang, Xiaohong Zhou, Bijiang Wan, Qiwang He   +7 more
wiley   +1 more source

The Therapeutic Effect of Phosphopeptide P140 Attenuates Inflammation Induced by Uric Acid Crystals in Gout Arthritis Mouse Model. [PDF]

Cells, 2022
Galvão I, Mastrippolito D, Talamini L, Aganetti M, Rocha V, Verdot C, Mendes V, de Oliveira VLS, Braga AD, Martins VD, de Faria AMC, Amaral FA, Georgel P, Vieira AT, Muller S.   +14 more
europepmc   +1 more source

Investigating the Relationship Between Dietary Antioxidant Index With Anthropometric Indices, Clinical Symptoms, Inflammatory Markers, Sleep Quality and Quality of Life in Patients With Rheumatoid Arthritis: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Rheumatoid arthritis (RA) is a chronic autoimmune disease causing joint inflammation, pain, and deformity, significantly impacting physical and mental well‐being. Sleep disturbances and obesity exacerbate symptoms, increasing disease severity.
Amirabbas Moarefian, Fatemeh Borazjani, Hadi Bazyar, Forough Nokhostin, Ahmad Zare Javid   +4 more
wiley   +1 more source

Post-ACL Reconstruction Graft Failure in Severe Gout Arthritis Patient. [PDF]

Int Med Case Rep J, 2021
Lubis AMT, Reksoprodjo AY, Kuncoro MW, Ifran NN.   +3 more
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Gout Arthritis During Admission for Decompensated Heart Failure-A Descriptive Analysis of Risk Factors, Treatment and Prognosis. [PDF]

Front Med (Lausanne), 2022
Ritter F, Franzeck F, Geisshardt J, Walker UA, Osthoff M.   +4 more
europepmc   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Construction and Validation of Plasma Protein‐Based Musculoskeletal Biological Age and Genetic and Environmental Risk Profiles

Aging Cell, Volume 25, Issue 8, August 2026.
We developed plasma protein‐based musculoskeletal aging clocks, MSKAge and MSKAgeMort, using UK Biobank proteomic data, and showed that MSKAgeAccel and MSKAgeMortAccel (in particular) predicted mortality, musculoskeletal disorders, and age‐related diseases effectively.
Yangdan Zhong, Maoyao Xia, Xunying Zhao, Yang Qu, Bowen Lei, Sirui Zhen, Tao Han, Rong Xiang, Jinyu Xiao, Xin Song, Xiaofeng Ma, Bin Yang, Di Zhang, Jinyu Zhou, Zilan Chen, Yuqi Pang, Ye Ju, Ting Liu, Zihao Li, Lu Long, Tao Zhang, Jiayuan Li, Mengyu Fan, Zuyun Liu, Xia Jiang   +24 more
wiley   +1 more source

Serum Uric acid level during the acute attacks of Gouty arthritis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2003
Background and Objective: Gout is a condition characterized by acute arthritis and hyperuricemia, but the prevalence of hyperuricemia and the level of serum uric acid (SUA) in acute gout is not known exactly.
B Heidari, KH Bijani, SH Savad Koohi, E Shafigh   +3 more
doaj  

CXCL5 activates CXCR2 in nociceptive sensory neurons to drive joint pain and inflammation in experimental gouty arthritis

Nature Communications
Gouty arthritis evokes joint pain and inflammation. Mechanisms driving gout pain and inflammation remain incompletely understood. Here we show that CXCL5 activates CXCR2 expressed on nociceptive sensory neurons to drive gout pain and inflammation.
Chengyu Yin, Boyu Liu, Zishan Dong, Sai Shi, Chenxing Peng, Yushuang Pan, Xiaochen Bi, Huimin Nie, Yunwen Zhang, Yan Tai, Qimiao Hu, Xuan Wang, Xiaomei Shao, Hailong An, Jianqiao Fang, Chuan Wang, Boyi Liu   +16 more
doaj   +1 more source