Results 71 to 80 of about 24,540 (201)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Single nucleotide polymorphisms associated with P2X7R function regulate the onset of gouty arthritis.

PLoS ONE, 2017
BackgroundGout is an inflammatory disease that is caused by the increased production of Interleukin-1β (IL-1β) stimulated by monosodium urate (MSU) crystals.
Jin-Hui Tao, Miao Cheng, Jiang-Ping Tang, Xiao-Juan Dai, Yong Zhang, Xiang-Pei Li, Qin Liu, Ya-Ling Wang   +7 more
doaj   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

The Omnicausal Model Reveals the Highly Polyfactorial Nature of Complex Diseases

Genetic Epidemiology, Volume 50, Issue 6, September 2026.
ABSTRACT Mendelian randomization (MR) is a human genetics method for inferring causal relationships between risk factors and diseases. A common focus of MR studies has been on the causal inference of a single risk factor on a single disease. This has led to the successful discovery of numerous causal risk factors for disease.
Carla Márquez‐Luna, Martin Tournaire, Ghislain Rocheleau, Ron Do, Marie Verbanck   +4 more
wiley   +1 more source

Pengaruh Kompres Hangat Jahe Merah Dan Effleurage Massage Dengan Minyak Zaitun Untuk Menurunkan Nyeri Gout Arthritis : Studi Kasus

Ners Muda
Gout arthritis merupakan penyakit peradangan sendi yang diakibatkan karena adanya penumpukan kristal monosodium urat. Manifestasi klinis pada gout arthritis yaitu nyeri kronis, teraba panas, adanya pembengkakan, kemerahan dan kaku dibagian persendian ...
Erika Amelia, Hikmi Muharromah Pratiwi, Lita Heni Kusumawardani   +2 more
doaj   +1 more source

Cushioned Insoles for First Metatarsophalangeal Joint Osteoarthritis: Protocol for the SOLE Randomised Controlled Trial

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Introduction First metatarsophalangeal (MTP) joint osteoarthritis (OA) is a common and disabling condition that causes substantial pain and impairs quality of life. Cushioned insoles have the potential to lower plantar pressures beneath the hallux and possibly reduce pain, but their clinical effectiveness has not been investigated.
Kade L. Paterson, Kim L. Bennell, Adam Bryant, Peixuan Li, Anurika P. De Silva, Sam Shearer, Rana S. Hinman   +6 more
wiley   +1 more source

When Joint Aspiration Fails: Point‐of‐Care Ultrasound for Diagnosing Chronic Gout in Prolonged Monoarthritis

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT Background A 34‐year‐old man presented to our primary care clinic with persistent pain and swelling of the right first metatarsophalangeal joint lasting 3 months. A previous clinic had suspected gout based on hyperuricemia, but urate‐lowering therapy was repeatedly withheld because of ongoing inflammation, resulting in prolonged symptoms ...
Takayuki Yamada
wiley   +1 more source

Factors affecting the frequency of arthritis attacks in patients with gout not receiving urate-lowering therapy (results of a pilot retrospective study)

Научно-практическая ревматология
Gout manifests as acute arthritis attacks, the frequency of which varies and is unpredictable.The aim of this study was to identify factors associated with the frequency of arthritis attacks in patients with gout who have not received urate-lowering ...
M. S. Eliseev, O. V. Zheliabina, E. V. Panina   +2 more
doaj   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

A Qualitative Exploration of the Multidimensional Influences on Physical Activity Among People With Arthritis

Musculoskeletal Care, Volume 24, Issue 3, September 2026.
ABSTRACT Objective To explore the individual, interpersonal, community, organisational, and policy‐level factors that influence physical activity among people with arthritis in England, using the Social Ecological Model as the analytical framework. Study Design Qualitative research.
Justin Webb, Heather Allison
wiley   +1 more source